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Showing 1–3 of 3 results
Advanced filters: Author: Avnika Bali Clear advanced filters

  • For pain signaling to be useful, sensory receptors must rapidly detect noxious stimuli and efficiently turn off once the threat has passed. Here, the authors uncover a critical role for the universal calcium sensor calmodulin in properly turning off the TRPA1 pain receptor.

    • Justin H. Sanders
    • Camila Garcia
    • Candice E. Paulsen
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • A study reveals a gut–brain sensory pathway through which the microbial component flagellin activates neuropod cells in the colon to signal the brain and reduce feeding in mice.

    • Winston W. Liu
    • Naama Reicher
    • Diego V. Bohórquez
    ResearchOpen Access
    Nature
    Volume: 645, P: 729-736

  • A drastic TRPA1 mutant was identified in patients with CRAMPT syndrome, but it has not been functionally characterized. Here, the authors find this mutant confers gain-of-function by co-assembling with wild type protein to form hyperactive channels.

    • Avnika Bali
    • Samantha P. Schaefer
    • Candice E. Paulsen
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15