A 33-year-old woman with a history of paroxysmal nocturnal hemoglobinuria (PNH) presented with abdominal pain, nausea and vomiting, accompanied by duodenal wall thickening seen on an abdominal CT scan and an ischemic-looking duodenal mucosa as visualized by endoscopy. She was diagnosed as having small bowel ischemia complicating PNH. Treatment with warfarin was started, but ischemic episodes recurred. Treatment with eculizumab was, therefore, proposed. This case highlights this rare gastrointestinal complication of PNH.
- Joana Torres
- Bénédicte De Vroey
- Jean-Frédéric Colombel
