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Maintenance olaparib after platinum-based chemotherapy for advanced/metastatic endometrial cancer: GINECO randomized phase IIb UTOLA trial

Single-agent maintenance PARP inhibition may represent an effective strategy for advanced/metastatic endometrial cancer treatment. Here this randomized phase IIb UTOLA trial evaluates the efficacy and safety of orally administered olaparib in female patients (n = 145) without progression following front-line platinum-based chemotherapy for advanced/metastatic endometrial cancer.

Florence Joly
Alexandra Leary
Jérôme Alexandre
ResearchOpen Access26 Aug 2025
Nature Communications

Volume: 16, P: 1-11
Prognostic value of steroid receptors after long-term follow-up of 2257 operable breast cancers

MF Pichon
P Broet
B Asselain
Research01 Jun 1996
British Journal of Cancer

Volume: 73, P: 1545-1551
Randomized trial comparing protracted infusion of 5-fluorouracil with weekly doxorubicin and cyclophosphamide with a monthly bolus FAC regimen in metastatic breast carcinoma (SPM90)

J-Y Pierga
M Jouve
P Pouillart
Research01 May 1998
British Journal of Cancer

Volume: 77, P: 1474-1479
First-line high-dose sequential chemotherapy with rG-CSF and repeated blood stem cell transplantation in untreated inflammatory breast cancer: toxicity and response (PEGASE 02 trial)

P Viens
T Palangié
P Pouillart
ResearchOpen Access10 Sept 1999
British Journal of Cancer

Volume: 81, P: 449-456
Prognostic value of persistent node involvement after neoadjuvant chemotherapy in patients with operable breast cancer

J-Y Pierga
E Mouret
P Pouillart
ResearchOpen Access14 Nov 2000
British Journal of Cancer

Volume: 83, P: 1480-1487
Increased serum p53 antibody levels indicate poor prognosis in patients with colorectal cancer

U Kressner
B Glimelius
G Lindmark
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 1848-1851
Increased p53 protein content of colorectal tumours correlates with poor survival

Y Remvikos
O Tominaga
G Thomas
Research01 Oct 1992
British Journal of Cancer

Volume: 66, P: 758-764
Low expression of bcl-2 in Brca1-associated breast cancers

P Freneaux
D Stoppa-Lyonnet
X Sastre-Garau
ResearchOpen Access24 Oct 2000
British Journal of Cancer

Volume: 83, P: 1318-1322
Cancer of the endometrium

A Brémond
A Bataillard
J Pigneux
ResearchOpen Access01 May 2001
British Journal of Cancer

Volume: 84, P: 31-36
The Centre H. Becquerel studies in inflammatory non metastatic breast cancer. Combined modality approach in 178 patients

B Chevallier
P Bastit
J D'Anjou
Research01 Mar 1993
British Journal of Cancer

Volume: 67, P: 594-601
Prognostic value of uPA and p53 accumulation measured by quantitative biochemical assays in 1245 primary breast cancer patients: a multicentre study

P Broët
F Spyratos
B Asselain
ResearchOpen Access09 Apr 1999
British Journal of Cancer

Volume: 80, P: 536-545
Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients

LLM Shek
W Godolphin
JJ Spinelli
Research01 Dec 1987
British Journal of Cancer

Volume: 56, P: 825-829
Overexpression of p53 mRNA in colorectal cancer and its relationship to p53 gene mutation

N el-Mahdani
J-C Vaillant
B Hermelin
Research01 Feb 1997
British Journal of Cancer

Volume: 75, P: 528-536
Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status

R A Bras-Gonçalves
C Rosty
M-F Poupon
ResearchOpen Access20 Jan 2000
British Journal of Cancer

Volume: 82, P: 913-923
High rate of extra-haematological toxicity compromises dose-dense sequential adjuvant chemotherapy for breast cancer

E Brain
C Levy
P Fumoleau
ResearchOpen Access18 Oct 2011
British Journal of Cancer

Volume: 105, P: 1480-1486
A prognostic score in histological node negative breast cancer

B Chevallier
V Mosseri
B Asselain
Research01 Mar 1990
British Journal of Cancer

Volume: 61, P: 436-440
Carcinoma of the cervix

M Resbeut
E Fondrinier
J Chauvergne
ResearchOpen Access01 May 2001
British Journal of Cancer

Volume: 84, P: 24-30
Multicentric evaluation of the MDR phenotype in leukemia

J-P Marie
S Huet
J Robert
Research01 Jul 1997
Leukemia

Volume: 11, P: 1086-1094
Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: the LMCE2 study

T Philip
R Ladenstein
P Biron
Research01 Jan 1993
British Journal of Cancer

Volume: 67, P: 119-127
Cyclical mastalgia as a marker of breast cancer susceptibility: results of a case-control study among French women

G Plu-Bureau
JC Thalabard
P Mauvais-Jarvis
Research01 Jun 1992
British Journal of Cancer

Volume: 65, P: 945-949
Frequent allelic losses at 11q24.1–q25 in young women with breast cancer: association with poor survival

M Gentile
K Olsen
S Wingren
ResearchOpen Access23 Apr 1999
British Journal of Cancer

Volume: 80, P: 843-849
Intrathecal treatment of neoplastic meningitis due to breast cancer with a slow-release formulation of cytarabine

K A Jaeckle
S Phuphanich
S B Howell
ResearchOpen Access16 Jan 2001
British Journal of Cancer

Volume: 84, P: 157-163
Hormone replacement therapy before breast cancer diagnosis significantly reduces the overall death rate compared with never-use among 984 breast cancer patients

H Jernström
J Frenander
H Olsson
ResearchOpen Access11 Jun 1999
British Journal of Cancer

Volume: 80, P: 1453-1458
Proton beam therapy for iris melanomas

L Lumbroso-Le Rouic
S Delacroix
L Desjardins
Research18 Nov 2006
Eye

Volume: 20, P: 1300-1305
¹²⁵I plaque brachytherapy for anterior uveal melanomas

L Lumbroso-Le Rouic
M Charif Chefchaouni
L Desjardins
Research05 Mar 2004
Eye

Volume: 18, P: 911-916
Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab

M Cizkova
M-E Dujaric
I Bieche
ResearchOpen Access23 Apr 2013
British Journal of Cancer

Volume: 108, P: 1807-1809
Second malignancies after breast cancer: the impact of different treatment modalities

Y M Kirova
Y De Rycke
A Fourquet
ResearchOpen Access12 Feb 2008
British Journal of Cancer

Volume: 98, P: 870-874
First-in-human phase I study of the DNA-repair inhibitor DT01 in combination with radiotherapy in patients with skin metastases from melanoma

C Le Tourneau
B Dreno
M Dutreix
ResearchOpen Access03 May 2016
British Journal of Cancer

Volume: 114, P: 1199-1205
Time-varying effect and long-term survival analysis in breast cancer patients treated with neoadjuvant chemotherapy

S Baulies
L Belin
F Reyal
ResearchOpen Access16 Jun 2015
British Journal of Cancer

Volume: 113, P: 30-36

Search

Maintenance olaparib after platinum-based chemotherapy for advanced/metastatic endometrial cancer: GINECO randomized phase IIb UTOLA trial

Prognostic value of steroid receptors after long-term follow-up of 2257 operable breast cancers

Randomized trial comparing protracted infusion of 5-fluorouracil with weekly doxorubicin and cyclophosphamide with a monthly bolus FAC regimen in metastatic breast carcinoma (SPM90)

First-line high-dose sequential chemotherapy with rG-CSF and repeated blood stem cell transplantation in untreated inflammatory breast cancer: toxicity and response (PEGASE 02 trial)

Prognostic value of persistent node involvement after neoadjuvant chemotherapy in patients with operable breast cancer

Increased serum p53 antibody levels indicate poor prognosis in patients with colorectal cancer

Increased p53 protein content of colorectal tumours correlates with poor survival

Low expression of bcl-2 in Brca1-associated breast cancers

Cancer of the endometrium

The Centre H. Becquerel studies in inflammatory non metastatic breast cancer. Combined modality approach in 178 patients

Prognostic value of uPA and p53 accumulation measured by quantitative biochemical assays in 1245 primary breast cancer patients: a multicentre study

Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients

Overexpression of p53 mRNA in colorectal cancer and its relationship to p53 gene mutation

Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status

High rate of extra-haematological toxicity compromises dose-dense sequential adjuvant chemotherapy for breast cancer

A prognostic score in histological node negative breast cancer

Carcinoma of the cervix

Multicentric evaluation of the MDR phenotype in leukemia

Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: the LMCE2 study

Cyclical mastalgia as a marker of breast cancer susceptibility: results of a case-control study among French women

Frequent allelic losses at 11q24.1–q25 in young women with breast cancer: association with poor survival

Intrathecal treatment of neoplastic meningitis due to breast cancer with a slow-release formulation of cytarabine

Hormone replacement therapy before breast cancer diagnosis significantly reduces the overall death rate compared with never-use among 984 breast cancer patients

Proton beam therapy for iris melanomas

¹²⁵I plaque brachytherapy for anterior uveal melanomas

Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab

Second malignancies after breast cancer: the impact of different treatment modalities

First-in-human phase I study of the DNA-repair inhibitor DT01 in combination with radiotherapy in patients with skin metastases from melanoma

Time-varying effect and long-term survival analysis in breast cancer patients treated with neoadjuvant chemotherapy

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