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Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Whole-genome sequencing of normal blood cells sampled from 241 adults is used to infer mosaic point mutations that are likely to have arisen during early embryogenesis, providing insight into how early cellular dynamics may affect adult tissues.

Young Seok Ju
Inigo Martincorena
Michael R. Stratton
Research22 Mar 2017
Nature

Volume: 543, P: 714-718
The influence of body mass index, age and gender on current illness: a cross-sectional study

B Jarrett
G J Bloch
D Hedges
Research15 Dec 2009
International Journal of Obesity

Volume: 34, P: 429-436
Mitochondrial factors with dual roles in death and survival

W-C Cheng
S B Berman
J M Hardwick
Reviews07 Aug 2006
Oncogene

Volume: 25, P: 4697-4705