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Showing 1–8 of 8 results

Advanced filters: Author: B M J Uitdehaag Clear advanced filters

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Here, the authors describe a potent and selective CK1a molecular glue degrader with a broad antiproliferative potency. Crystallographic data provide rationale for the high degradation efficacy displayed by this compound.

Gisele Nishiguchi
Lauren G. Mascibroda
Zoran Rankovic
ResearchOpen Access16 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase

Helen Michels
Renée I. Seinstra
Ellen A. A. Nollen
ResearchOpen Access20 Dec 2016
Scientific Reports

Volume: 6, P: 1-8
Cytokine gene polymorphism in human disease: on-line databases, Supplement 1

J Bidwell
L Keen
S D’Alfonso
Reviews18 Apr 2001
Genes & Immunity

Volume: 2, P: 61-70
Use of health information in air pollution health research: Past successes and emerging needs

George D Thurston
Marni Y V Bekkedal
Mark J Utell
Research10 Sept 2008
Journal of Exposure Science & Environmental Epidemiology

Volume: 19, P: 45-58
Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonβ therapy in multiple sclerosis

S Vosslamber
L F van der Voort
C L Verweij
Research07 Apr 2011
Genes & Immunity

Volume: 12, P: 466-472
Erratum: Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonb therapy in multiple sclerosis

S Vosslamber
L F van der Voort
C L Verweij
Amendments and Corrections19 Jul 2012
Genes & Immunity

Volume: 13, P: 443
Antioxidants and polyunsaturated fatty acids in multiple sclerosis

M E van Meeteren
C E Teunissen
E A F van Tol
Reviews24 Aug 2005
European Journal of Clinical Nutrition

Volume: 59, P: 1347-1361
MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia

K Canté-Barrett
J A P Spijkers-Hagelstein
J P P Meijerink
ResearchOpen Access22 Apr 2016
Leukemia

Volume: 30, P: 1832-1843