Infantile hypertrophic pyloric stenosis (IHPS) is a common condition in neonates with a largely unknown aetiology. In this article, Babette Peeters and colleagues provide an overview of molecular and genetic studies in patients with isolated IHPS and categorize the various syndromes associated with IHPS. The authors hope this article will provide a basis for future studies in IHPS and stimulate researchers to use the results of extreme phenotype studies in evaluation of their results in isolated IHPS.
- Babette Peeters
- Marc A. Benninga
- Raoul C. M. Hennekam
