Nature Search

Biocatalytic stereocontrolled head-to-tail cyclizations of unbiased terpenes as a tool in chemoenzymatic synthesis

Terpene synthesis is limited by the current availability of natural cyclic building blocks. In this study, the authors employ squalene-hopene cyclases in the chemoenzymatic synthesis of head-to-tail fused terpenes and generate ten chiral scaffolds with >99% ee and de, at up to decagram scale.

Andreas Schneider
Thomas B. Lystbæk
Bernhard Hauer
ResearchOpen Access10 Jun 2024
Nature Communications

Volume: 15, P: 1-10
Approaching the standard quantum limit of mechanical torque sensing

Cavity optomechanics enables measurement of torque at levels unattainable by previous techniques, but the main obstacle to improved sensitivity is thermal noise. Here the authors present cryogenic measurement of a cavity-optomechanical torsional resonator with unprecedented torque sensitivity of 2.9 yNm/√Hz.

P. H. Kim
B. D. Hauer
J. P. Davis
ResearchOpen Access20 Oct 2016
Nature Communications

Volume: 7, P: 1-6
Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

Infection or chronic inflammation is a risk factor for childhood B-cell precursor acute lymphoblastic leukemia. Here, the authors show that the DNA editing enzyme AID is expressed in infected B cells but using genetic mouse models show that it does not contribute to leukemia pathogenesis.

Guillermo Rodríguez-Hernández
Friederike V. Opitz
Arndt Borkhardt
ResearchOpen Access05 Dec 2019
Nature Communications

Volume: 10, P: 1-10
Magnetic actuation and feedback cooling of a cavity optomechanical torque sensor

Although optomechanics enables precision metrology, measurements beyond mechanical properties often require hybrid devices. Here, Kim et al. demonstrate that a ferromagnetic needle integrated with a torsional resonator can determine the magnetic properties and amplify or cool the resonator motion.

P. H. Kim
B. D. Hauer
J. P. Davis
ResearchOpen Access07 Nov 2017
Nature Communications

Volume: 8, P: 1-6
Transplacental Passage of Red Cells in Man

RONALD FINN
C. A. CLARKE
D. LEHANE
Research03 Jun 1961
Nature

Volume: 190, P: 922-923
Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA_I

Patricia A. Reichel
William C. Merrick
Michael B. Mathews
Research17 Jan 1985
Nature

Volume: 313, P: 196-200
Demonstration of Nucleases on Mammalian Skin Surface and in Saline Extracts of Hair

JOSEPH TABACHNICK
RICHARD FREED
Research03 Jun 1961
Nature

Volume: 190, P: 921-922
Involvement of circular intermediates in the transfer of T-DNA from Agrobacterium tumefaciens to plant cells

Zdena Koukolíková-Nicola
Raymond D. Shillito
Patricia Zembryski
Research17 Jan 1985
Nature

Volume: 313, P: 191-196
Sucrose Induction of Hepatic Hyperplasia in the Rat

A. E. BENDER
K. B. DAMJI
J. YUDKIN
Research25 Aug 1972
Nature

Volume: 238, P: 461-462
Hepatic stellate cells control liver zonation, size and functions via R-spondin 3

Hepatic stellate cells regulate hepatocyte functions via R-spondin 3.

Atsushi Sugimoto
Yoshinobu Saito
Robert F. Schwabe
ResearchOpen Access12 Mar 2025
Nature

Volume: 640, P: 752-761
Milestone in predicting core plasma turbulence: successful multi-channel validation of the gyrokinetic code GENE

Plasma turbulence is the main driver to deteriorate the performance of fusion power plants. This work presents an unprecedented comparison of plasma turbulence between experiment and simulation, proving that the gyrokinetic model GENE reached a high level of maturity to predict core turbulence.

Klara Höfler
Tobias Görler
S. Zoletnik
ResearchOpen Access15 Mar 2025
Nature Communications

Volume: 16, P: 1-11
A New Scientific Serial¹

G. B. H.
News12 Jun 1890
Nature

Volume: 42, P: 157-158
Signs of consciousness in AI: Can GPT-3 tell how smart it really is?

Ljubiša Bojić
Irena Stojković
Zorana Jolić Marjanović
ResearchOpen Access02 Dec 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-15
Effect of energetic ions on edge-localized modes in tokamak plasmas

Edge-localized plasma modes in a tokamak can damage its innermost wall. Simulations now show that fast ions can modify the spatio-temporal structure of these modes. These effects need to be considered in the optimization of control techniques.

J. Dominguez-Palacios
S. Futatani
M. Zuin
ResearchOpen Access06 Jan 2025
Nature Physics

Volume: 21, P: 43-51
Engineered cytochrome P450 for direct arylalkene-to-ketone oxidation via highly reactive carbocation intermediates

The direct regioselective oxidation of internal alkenes to ketones poses an important synthetic challenge. Now, directed evolution of a cytochrome P450 enzyme affords a ketone synthase that can efficiently oxidize internal arylalkenes directly to ketones with high chemo- and regioselectivity.

Sebastian Gergel
Jordi Soler
Stephan C. Hammer
ResearchOpen Access13 Jul 2023
Nature Catalysis

Volume: 6, P: 606-617
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Observation of magnetic islands in tokamak plasmas during the suppression of edge-localized modes

The suppression of edge-localized modes in tokamak plasmas is crucial to prevent them from damaging the walls of the chamber. Now experiments confirm the role that magnetic islands play in suppressing these detrimental modes.

Matthias Willensdorfer
Verena Mitterauer
S. Zoletnik
ResearchOpen Access28 Oct 2024
Nature Physics

Volume: 20, P: 1980-1988
Vibronic origin of long-lived coherence in an artificial molecular light harvester

Two-dimensional spectroscopy revealed oscillatory signals in photosynthesis’ exciton dynamics, but crowded spectra impede the identification of what sustains the oscillations. Here the authors probe an J-aggregate, whose uncongested response shows that vibronic coupling is responsible for the sustained coherence.

James Lim
David Paleček
Jürgen Hauer
ResearchOpen Access09 Jul 2015
Nature Communications

Volume: 6, P: 1-7
Loop dynamics and the evolution of enzyme activity

Enzyme conformational plasticity plays an important part in expanding the functional diversity of a limited repertoire of sequences. This Review discusses the role of flexible loops in enzyme evolution, focusing on both examples from natural evolution and engineering success stories.

Marina Corbella
Gaspar P. Pinto
Shina C. L. Kamerlin
Reviews24 May 2023
Nature Reviews Chemistry

Volume: 7, P: 536-547
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
Direct observation of the dead-cone effect in quantum chromodynamics

The direct measurement of the QCD dead cone in charm quark fragmentation is reported, using iterative declustering of jets tagged with a fully reconstructed charmed hadron.

S. Acharya
D. Adamova
N. Zurlo
ResearchOpen Access18 May 2022
Nature

Volume: 605, P: 440-446
Measurement of anti-³He nuclei absorption in matter and impact on their propagation in the Galaxy

Measurements of the inelastic cross section of anti-³He allow the estimation of the transparency of the Milky Way to the propagation of these light antinuclei produced in either cosmic-ray collisions or annihilation of dark-matter particles.

S. Acharya
D. Adamová
N. Zurlo
ResearchOpen Access12 Dec 2022
Nature Physics

Volume: 19, P: 61-71
Genomic determinants of therapy response in ETV6::RUNX1 leukemia

Laura Oksa
Sanni Moisio
Merja Heinäniemi
ResearchOpen Access09 Jul 2025
Leukemia

Volume: 39, P: 2125-2139
Unveiling the strong interaction among hadrons at the LHC

Correlations in momentum space between hadrons created by ultrarelativistic proton–proton collisions at the CERN Large Hadron Collider provide insights into the strong interaction, particularly the short-range dynamics of hyperons—baryons that contain strange quarks.

S. Acharya
D. Adamová
N. Zurlo
ResearchOpen Access09 Dec 2020
Nature

Volume: 588, P: 232-238
Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope

Single-molecule fluorescence currently requires specialized imaging equipment due to the low signal of a single emitter. Here the authors introduce NanoAntennas with Cleared HOtSpots (NACHOS) to boost the signal sufficient for detection of a single emitter by a smartphone, opening the door to point-of-care applications.

Kateryna Trofymchuk
Viktorija Glembockyte
Philip Tinnefeld
ResearchOpen Access11 Feb 2021
Nature Communications

Volume: 12, P: 1-8
“I can migrate, but why should I?”—voluntary non-migration despite creeping environmental risks

Bishawjit Mallick
Chup Priovashini
Jochen Schanze
ResearchOpen Access25 Jan 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-14
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism

Selective pharmacological blockade of forebrain excitatory AMPA receptors that express the TARP γ-8 subunit enables antiepileptic therapy in rodent models of epilepsy without inducing motor impairments associated with currently used antiepileptic drugs.

Akihiko S Kato
Kevin D Burris
Jeffrey M Witkin
Research07 Nov 2016
Nature Medicine

Volume: 22, P: 1496-1501
Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity

Using an unbiased genetic screen in mice, Hartmut Geiger et al. found that the thrombomodulin–activated protein C pathway, which controls blood coagulation among other functions, also protects from radiation damage. Administration of a recombinant variant of thrombomodulin or of recombinant activated protein C protected mice from total body irradiation, pointing to potential therapeutic applications.

Hartmut Geiger
Snehalata A Pawar
Martin Hauer-Jensen
Research24 Jun 2012
Nature Medicine

Volume: 18, P: 1123-1129
Rethinking Jacques-Louis David’s Marat assassiné through material evidences

Catherine Defeyt
Dominique Marechal
David Strivay
ResearchOpen Access31 Jan 2023
Heritage Science

Volume: 11, P: 1-13
Virtual reality-based training to augment recovery of hand dexterity after surgery for degenerative cervical myelopathy

Viprav B. Raju
Roxanne Hauer
Aditya Vedantam
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Drivers’ behavior confronting fixed and point-to-point speed enforcement camera: agent-based simulation and translation to crash relative risk change

Seyed Amir Ahmad Safavi-Naini
Shayan Sobhani
Farshad Farzadfar
ResearchOpen Access22 Jan 2024
Scientific Reports

Volume: 14, P: 1-11
Genetic screening confirms heterozygous mutations in ACAN as a major cause of idiopathic short stature

Nadine N. Hauer
Heinrich Sticht
Christian T. Thiel
ResearchOpen Access22 Sept 2017
Scientific Reports

Volume: 7, P: 1-6
Androgen receptors in the neo-natal period: evidence for some “physiological” androgen resistance in male infants

CH Sultan
A Terraza
J Bertsand
Research01 Jan 1981
Pediatric Research

Volume: 15, P: 88
Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging

Organ Mapping Antibody Panels are a community-led initiative to create standardized antibody panels for multiplexed spatial imaging.

Ellen M. Quardokus
Diane C. Saunders
Andrea J. Radtke
ResearchOpen Access19 Jul 2023
Nature Methods

Volume: 20, P: 1174-1178
Quantification of Detergents Complexed with Membrane Proteins

Vincent Chaptal
Frédéric Delolme
Pierre Falson
ResearchOpen Access08 Feb 2017
Scientific Reports

Volume: 7, P: 1-12
Industrial biocatalysis today and tomorrow

A. Schmid
J. S. Dordick
B. Witholt
Reviews11 Jan 2001
Nature

Volume: 409, P: 258-268
Meeting the looming policy challenge of sea-level change and human migration

Minimizing the adverse consequences of sea-level change presents a key societal challenge. New modelling is necessary to examine the implications of global policy decisions that determine future greenhouse gas emissions and local policies around coastal risk that influence where and how we live.

D. J. Wrathall
V. Mueller
K. Warner
Comments & Opinion26 Nov 2019
Nature Climate Change

Volume: 9, P: 898-901
Nonlinear excitation of energetic particle driven geodesic acoustic mode by resonance overlap with Alfvén instability in ASDEX Upgrade

Hao Wang
Philipp Lauber
S. Zoletnik
ResearchOpen Access07 Jan 2025
Scientific Reports

Volume: 15, P: 1-11
Pathology of acute sub-lethal or near-lethal irradiation of nonhuman primates prophylaxed with the nutraceutical, gamma tocotrienol

Vijay K. Singh
Stephen Y. Wise
Thomas M. Seed
ResearchOpen Access10 Jun 2024
Scientific Reports

Volume: 14, P: 1-20
Publisher Correction: Direct observation of the dead-cone effect in quantum chromodynamics

S. Acharya
D. Adamova
N. Zurlo
Amendments and CorrectionsOpen Access07 Jul 2022
Nature

Volume: 607, P: E22
Publisher Correction: Unveiling the strong interaction among hadrons at the LHC

S. Acharya
D. Adamová
N. Zurlo
Amendments and CorrectionsOpen Access15 Jan 2021
Nature

Volume: 590, P: E13
Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16^INK4A as upstream regulators of Myc

Kirsten Haas
Peter Staller
Tarik Möröy
Research10 Jul 1997
Oncogene

Volume: 15, P: 179-192
The Hypnotic Actions of the Fatty Acid Amide, Oleamide

Wallace B Mendelson
Anthony S Basile
Research01 Nov 2001
Neuropsychopharmacology

Volume: 25, P: S36-S39
A guideline on the molecular ecosystem regulating ferroptosis

In this Review, Dai, Stockwell, Kroemer, Tang and colleagues offer a comprehensive discussion of the molecular regulation of ferroptosis and highlight how this may be potentially leveraged for therapeutic benefit for disease treatment.

Enyong Dai
Xin Chen
Daolin Tang
Reviews29 Feb 2024
Nature Cell Biology

Volume: 26, P: 1447-1457
Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis

Marta Isidro-Hernández
Andrea Mayado
Isidro Sánchez-García
ResearchOpen Access05 Nov 2020
Scientific Reports

Volume: 10, P: 1-14
New insights into the clinical and molecular spectrum of the novel CYFIP2-related neurodevelopmental disorder and impairment of the WRC-mediated actin dynamics

Anaïs Begemann
Heinrich Sticht
Anita Rauch
ResearchOpen Access05 Nov 2020
Genetics in Medicine

Volume: 23, P: 543-554
Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira

Jungmoo Huh
Jin Zhang
Nirmal D. Pugh
ResearchOpen Access19 Sept 2022
Scientific Reports

Volume: 12, P: 1-13
CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation

G Della Torre
B Pasini
M A Pierotti
ResearchOpen Access11 Sept 2001
British Journal of Cancer

Volume: 85, P: 836-844
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

The Human BioMolecular Atlas Program (HuBMAP) presents its production phase: the generation of spatial maps of functional tissue units across organs from diverse populations and the creation of tools and infrastructure to advance biomedical research.

Sanjay Jain
Liming Pei
Michael P. Snyder
Reviews19 Jul 2023
Nature Cell Biology

Volume: 25, P: 1089-1100
Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol

Vijay K. Singh
Stephen Y. Wise
Thomas M. Seed
ResearchOpen Access08 Mar 2024
Scientific Reports

Volume: 14, P: 1-18

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