The authors used chronic two-photon calcium imaging to record activity in primary whisker somatosensory cortex neurons projecting to secondary somatosensory or primary motor cortex while mice learned a texture discrimination task. Learning-related changes in primary somatosensory cortex enhanced sensory representations in a pathway-specific manner and provided downstream areas with task-relevant information for behavior.
- Jerry L Chen
- David J Margolis
- Fritjof Helmchen
