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Advanced filters: Author: Bailun Li Clear advanced filters

  • It is still a challenge to accurately identify off-target endonuclease edits. Here the authors report PEAC-seq using a Prime Editor to insert a tag to the editing sites and enrich the tagged regions with site-specific primers for sequencing: they show that PEAC-seq could identify DNA translocations.

    • Zhenxing Yu
    • Zhike Lu
    • Lijia Ma
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13