Shuping Li et al. show that angiogenin and its receptor plexin-B2 regulate the stemness of prostate cancer stem cells. Monoclonal antibodies of angiogenin and plexin-B2 sensitize prostate cancer stem cells to chemotherapy, highlighting the targeting potential of this regulation.
- Shuping Li
- Kevin A. Goncalves
- Guo-fu Hu