Propagation of neural progenitor cells on silk-based macroporous scaffolds. The potential for macroporous 3D silk fibroin scaffolds for the propagation of human neural progenitor cells is investigated. It is found that microstructure and porosity of the fabricated silk fibroin scaffolds allow for sustained viability and proliferation of human neural progenitors. We also find that although fibroin scaffolds from mulberry and non-mulberry silks are cytocompatible, non-mulberry silk matrices appeared to promote slightly increased cell proliferation and matrix deposition.
- Bano Subia
- Raj R Rao
- Subhas C Kundu
