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Nature Immunology (2)
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8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins

The replication accessory proteins PCNA and RPA are unexpectedly able to stimulate the activity of some of the polymerases that catalyse DNA synthesis. It is speculated that the ability of some polymerases to have their activity enhanced in this way sets up a hierarchy of polymerase utilization at DNA lesions.

Giovanni Maga
Giuseppe Villani
Ulrich Hübscher
Research16 May 2007
Nature

Volume: 447, P: 606-608
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

Ahmad Faili
Said Aoufouchi
Claude-Agnès Reynaud
Research29 Jul 2002
Nature Immunology

Volume: 3, P: 815-821
Multiple layers of B cell memory with different effector functions

Immunization elicits B cell memory and short- and long-term antibody-secreting plasma cells. Weill and colleagues show that long-term IgM⁺ and IgG⁺ memory B cells can persist in germinal centers and undergo different fates after antigenic rechallenge.

Ismail Dogan
Barbara Bertocci
Jean-Claude Weill
Research25 Oct 2009
Nature Immunology

Volume: 10, P: 1292-1299