Nature Search

Complexes of tubulin oligomers and tau form a viscoelastic intervening network cross-bridging microtubules into bundles

X-ray scattering and electron microscopy are used in concert to show that complexes of tubulin oligomers and tau are building blocks of an intervening network that cross-bridge microtubules into bundles with the same linear geometry observed in neurons.

Phillip A. Kohl
Chaeyeon Song
Cyrus R. Safinya
ResearchOpen Access15 Mar 2024
Nature Communications

Volume: 15, P: 1-15
Recent co-evolution of two pandemic plant diseases in a multi-hybrid swarm

Analysing the evolutionary history of two recent populations of a pathogenic fungus that infects wheat and ryegrasses, the authors show how recombination and selection on standing genetic variation contributed to adaptation to the new hosts.

Mostafa Rahnama
Bradford Condon
Mark L. Farman
ResearchOpen Access09 Nov 2023
Nature Ecology & Evolution

Volume: 7, P: 2055-2066
Facile synthesis of block copolypeptides of defined architecture

Timothy J. Deming
Research27 Nov 1997
Nature

Volume: 390, P: 386-389
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

A chemical probe BI-9321 for the PWWP1 domain of NSD3 and its inactive analog were identified. BI-9321 binds to the methyl-lysine binding site, reduces the association of NSD3 with chromatin and inhibits proliferation of acute myeloid leukemia cells.

Jark Böttcher
David Dilworth
Darryl B. McConnell
Research08 Jul 2019
Nature Chemical Biology

Volume: 15, P: 822-829
CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae

In this work, Huang and colleagues describe variation in DNA repair outcomes due to distinct repair mechanisms following CRISPR targeting of different loci in the plant pathogenic fungus Magnaporthe oryzae.

Jun Huang
David Rowe
David E. Cook
ResearchOpen Access22 Nov 2022
Nature Communications

Volume: 13, P: 1-18
Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate

While cellular stress shuts down translation, how protein degradation occurs with stress is incompletely understood. The authors describe a stress-induced phase separated organelle that mediates ubiquitin-independent degradation in the proteasome.

Daniel C. Carrettiero
Maria C. Almeida
Kenneth S. Kosik
ResearchOpen Access02 Jun 2022
Nature Communications

Volume: 13, P: 1-16
Maximal exercise response of paraplegic wheelchair road racers

R A Cooper
S M Horvath
R E Williams
Research01 Aug 1992
Spinal Cord

Volume: 30, P: 573-581
Improving R&D productivity

Using a novel metric that links investment in drug research and development (R&D) to output in terms of revenue from the resultant drugs, this article analyses trends in R&D productivity overall and in specific therapeutic areas, and discusses strategies for improvement.

Katarzyna Smietana
Leeland Ekstrom
Martin Møller
Comments & Opinion12 Jun 2015
Nature Reviews Drug Discovery

Volume: 14, P: 455-456
Lifshitz transition from valence fluctuations in YbAl₃

How the electronic structure of a mixed-valence system changes with respect to local chemical environment remains elusive. Here, Chatterjee et al. show that valence fluctuations of YbAl₃ can lead to dramatic changes in the Fermi surface topology in reciprocal space.

Shouvik Chatterjee
Jacob P. Ruf
Kyle M. Shen
ResearchOpen Access11 Oct 2017
Nature Communications

Volume: 8, P: 1-7
Naturally occurring 2D semiconductor with antiferromagnetic ground state

Barbara Pacakova
Bera Lahtinen-Dahl
Jon Otto Fossum
ResearchOpen Access13 May 2025
npj 2D Materials and Applications

Volume: 9, P: 1-8
Plasmon-driven carbon–fluorine (C(sp³)–F) bond activation with mechanistic insights into hot-carrier-mediated pathways

The cleavage of C–F bonds through hydrodefluorination is challenging and has been traditionally limited to unsaturated fluorocarbons. Now, a simple plasmonic approach based on the use of aluminium nanocrystal-supported palladium nanoparticles is introduced to effectively upgrade fluoromethane under visible light.

Hossein Robatjazi
Junwei Lucas Bao
Naomi J. Halas
Research08 Jun 2020
Nature Catalysis

Volume: 3, P: 564-573
An actinide milestone

A complex featuring a uranium(VI) terminal nitride functional group has been isolated through mild oxidation, and shown to be highly reactive. Under photolysis, it converts into a compound that is capable of C–H bond activation.

Trevor W. Hayton
News & Views05 May 2013
Nature Chemistry

Volume: 5, P: 451-452
Real-time qPCR improves meningitis pathogen detection in invasive bacterial-vaccine preventable disease surveillance in Fiji

Eileen M. Dunne
Silivia Mantanitobua
Fiona M. Russell
ResearchOpen Access23 Dec 2016
Scientific Reports

Volume: 6, P: 1-7
Appressorium-mediated plant infection by Magnaporthe oryzae is regulated by a Pmk1-dependent hierarchical transcriptional network

Comparative RNA-seq, ChIP–seq and quantitative phosphoproteomics reveal how the blast fungus uses the Pmk1 MAP kinase to regulate a network of transcription factors that orchestrate the complex transcriptome changes necessary for infecting rice plants.

Míriam Osés-Ruiz
Neftaly Cruz-Mireles
Nicholas J. Talbot
Research27 Oct 2021
Nature Microbiology

Volume: 6, P: 1383-1397
The rice blast resistance gene Ptr encodes an atypical protein required for broad-spectrum disease resistance

Genes that confer resistance to plant pathogens such as rice blast disease typically encode NLR-type receptor proteins. Here, Zhao et al. describe a new resistance locus that encodes a non-NLR Armadillo repeat protein required for broad-spectrum resistance in rice.

Haijun Zhao
Xueyan Wang
Yinong Yang
ResearchOpen Access23 May 2018
Nature Communications

Volume: 9, P: 1-12
Two distinct secretion systems facilitate tissue invasion by the rice blast fungus Magnaporthe oryzae

Understanding how fungal pathogens deliver proteins to diverse plant compartments is critical for developing disease control. Giraldo et al. demonstrate that the blast fungus possesses distinct secretion systems for proteins targeted to compartments inside or outside living rice cells.

Martha C. Giraldo
Yasin F. Dagdas
Barbara Valent
ResearchOpen Access18 Jun 2013
Nature Communications

Volume: 4, P: 1-12
Industrial hemp biomass negatively affected by herbicide drift from corn and soybean herbicides

Milos Zaric
Bruno Canella Vieira
Greg R. Kruger
ResearchOpen Access15 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Developing trends in nanomaterials and their environmental implications

Nanotechnology is advancing at an accelerated pace in applications and novel nanomaterials. To become an enabling technology for a more sustainable society, we identify and assess nanomaterials and applications trends with potentially significant environmental implications.

Arturo A. Keller
Alex Ehrens
Bernd Nowack
Comments & Opinion06 Jun 2023
Nature Nanotechnology

Volume: 18, P: 834-837
Filamentous plant pathogen effectors in action

Giraldo and Valent review the latest research into the molecular and cellular biology of the effectors that are secreted during biotrophic invasion of plant cells by eukaryotic filamentous pathogens, with an emphasis on results obtained by live-cell imaging of effector dynamics during natural plant invasions.

Martha C. Giraldo
Barbara Valent
Reviews16 Oct 2013
Nature Reviews Microbiology

Volume: 11, P: 800-814
Underground life for rice foe

We still have much to learn about the world's chief disease of rice — rice blast. That's clear from the finding that the culprit not only infects aerial plant tissues but can also invade roots like a typical root pathogen.

Barbara Valent
News & Views29 Sept 2004
Nature

Volume: 431, P: 516-517
Nanobiotechnology-based strategies for enhanced crop stress resilience

When plants are under stress, the over-accumulation of reactive oxygen species (ROS) leads to phytotoxicity and growth inhibition. This Review examines the current approaches of applying ROS-scavenging and ROS-triggering nanomaterials to plants to enhance stress resistance and explores their delivery pathways.

Lijuan Zhao
Tonghao Bai
Jason C. White
Reviews03 Oct 2022
Nature Food

Volume: 3, P: 829-836
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

BET bromodomain inhibitors are being explored as potential therapeutics in cancer; here, AML cells are shown to evade sensitivity to BET inhibition through rewiring the transcriptional regulation of BRD4 target genes such as MYC in a process that is facilitated by suppression of PRC2 and WNT signalling activation.

Philipp Rathert
Mareike Roth
Johannes Zuber
Research14 Sept 2015
Nature

Volume: 525, P: 543-547
The ability of heart rate or perceived exertion to predict oxygen uptake varies across exercise modes in persons with tetraplegia

Jessie R. Shea
Barbara L. Shay
Kristine C. Cowley
Research30 Aug 2021
Spinal Cord

Volume: 59, P: 1247-1255
Drastic enhancement of magnetic critical temperature and amorphization in topological magnet EuSn₂P₂ under pressure

Wenli Bi
Trenton Culverhouse
Yogesh K. Vohra
ResearchOpen Access19 Apr 2022
npj Quantum Materials

Volume: 7, P: 1-8
Variation in the concentration and regional distribution of magnetic nanoparticles in human brains, with and without Alzheimer’s disease, from the UK

Jessica Hammond
Barbara A. Maher
David Allsop
ResearchOpen Access30 Apr 2021
Scientific Reports

Volume: 11, P: 1-13
Immune system correlates of extensive limb swelling in response to conjugated pneumococcal vaccination

Mike Recher
Julia R. Hirsiger
Christoph T. Berger
ResearchOpen Access18 May 2018
npj Vaccines

Volume: 3, P: 1-4
Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia

Sebastian Kollmann
Eva Grundschober
Veronika Sexl
ResearchOpen Access24 Jan 2019
Leukemia

Volume: 33, P: 1583-1597
Engraftment in NSG_SCF mice correlates with the WHO category and prognosis in systemic mastocytosis

Michael Willmann
Barbara Peter
Peter Valent
ResearchOpen Access14 Mar 2023
Leukemia

Volume: 37, P: 1162-1165
Four patients with a history of acute exacerbations of COPD: implementing the CHEST/Canadian Thoracic Society guidelines for preventing exacerbations

Ioanna Tsiligianni
Donna Goodridge
Jean Bourbeau
ReviewsOpen Access07 May 2015
npj Primary Care Respiratory Medicine

Volume: 25, P: 1-7
Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia

Gregor Eisenwort
Irina Sadovnik
Peter Valent
Research30 Mar 2021
Leukemia

Volume: 35, P: 3176-3187
Pharmacologic inhibition of STAT5 in acute myeloid leukemia

Bettina Wingelhofer
Barbara Maurer
Richard Moriggl
ResearchOpen Access02 Feb 2018
Leukemia

Volume: 32, P: 1135-1146
Cognitive Mechanisms of Treatment in Depression

Jonathan P Roiser
Rebecca Elliott
Barbara J Sahakian
Reviews05 Oct 2011
Neuropsychopharmacology

Volume: 37, P: 117-136

Search

Complexes of tubulin oligomers and tau form a viscoelastic intervening network cross-bridging microtubules into bundles

Recent co-evolution of two pandemic plant diseases in a multi-hybrid swarm

Facile synthesis of block copolypeptides of defined architecture

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae

Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate

Maximal exercise response of paraplegic wheelchair road racers

Improving R&D productivity

Lifshitz transition from valence fluctuations in YbAl₃

Naturally occurring 2D semiconductor with antiferromagnetic ground state

Plasmon-driven carbon–fluorine (C(sp³)–F) bond activation with mechanistic insights into hot-carrier-mediated pathways

An actinide milestone

Real-time qPCR improves meningitis pathogen detection in invasive bacterial-vaccine preventable disease surveillance in Fiji

Appressorium-mediated plant infection by Magnaporthe oryzae is regulated by a Pmk1-dependent hierarchical transcriptional network

The rice blast resistance gene Ptr encodes an atypical protein required for broad-spectrum disease resistance

Two distinct secretion systems facilitate tissue invasion by the rice blast fungus Magnaporthe oryzae

Industrial hemp biomass negatively affected by herbicide drift from corn and soybean herbicides

Developing trends in nanomaterials and their environmental implications

Filamentous plant pathogen effectors in action

Underground life for rice foe

Nanobiotechnology-based strategies for enhanced crop stress resilience

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

The ability of heart rate or perceived exertion to predict oxygen uptake varies across exercise modes in persons with tetraplegia

Drastic enhancement of magnetic critical temperature and amorphization in topological magnet EuSn₂P₂ under pressure

Variation in the concentration and regional distribution of magnetic nanoparticles in human brains, with and without Alzheimer’s disease, from the UK

Immune system correlates of extensive limb swelling in response to conjugated pneumococcal vaccination

Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia

Engraftment in NSG_SCF mice correlates with the WHO category and prognosis in systemic mastocytosis

Four patients with a history of acute exacerbations of COPD: implementing the CHEST/Canadian Thoracic Society guidelines for preventing exacerbations

Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia

Pharmacologic inhibition of STAT5 in acute myeloid leukemia

Cognitive Mechanisms of Treatment in Depression

Search

Quick links

Search

Filter By:

Search

Quick links