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Showing 1–3 of 3 results

Advanced filters: Author: Barbara Varnum-Finney Clear advanced filters

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

Barbara Varnum-Finney
Lanwei Xu
Irwin D. Bernstein
Research01 Nov 2000
Nature Medicine

Volume: 6, P: 1278-1281
Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

Brian J Nickoloff
Barbara A Osborne
Lucio Miele
Reviews03 Oct 2003
Oncogene

Volume: 22, P: 6598-6608
Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics

Here, the authors use single cell RNA-sequencing to generate an atlas of signaling interactions regulating embryonic hematopoietic stem cell (HSC) development and apply this knowledge to engineer a niche sufficient to support HSC maturation in vitro.

Brandon Hadland
Barbara Varnum-Finney
Irwin D. Bernstein
ResearchOpen Access24 Mar 2022
Nature Communications

Volume: 13, P: 1-17