Nature Search

Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and associated humans in the Netherlands

SARS-CoV-2 was detected in mink farms in the Netherlands in the first wave of the pandemic with evidence of human-to-mink and mink-to-human transmission. Here, the authors investigate this outbreak using phylodynamic analysis and show that personnel links and spatial proximity are predictors of transmission between farms.

Lu Lu
Reina S. Sikkema
Marion P. G. Koopmans
ResearchOpen Access23 Nov 2021
Nature Communications

Volume: 12, P: 1-12
Diabetes type II, other medical conditions and pancreatic cancer risk: a prospective study in The Netherlands

P Eijgenraam
M M Heinen
P A van den Brandt
ResearchOpen Access22 Oct 2013
British Journal of Cancer

Volume: 109, P: 2924-2932
Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner

ZEB2 transcription factor is increased in a subset of cardiomyocytes during stress to induce cardioprotective effects after injury. Here the authors show that therapeutic delivery of ZEB2 prevents cardiac dysfunction after ischemic damage and promotes the activation of pro-angiogenic signals.

Monika M. Gladka
Arwa Kohela
Eva van Rooij
ResearchOpen Access04 Jan 2021
Nature Communications

Volume: 12, P: 1-16
Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair

Molenaar et al. use scRNA-seq to profile cardiac cell gene expression changes at three time points following ischemic injury. They observe that B2M is secreted by cardiomyocytes following injury, promoting scar formation. This data may be useful in finding therapeutic targets for cardiac repair

Bas Molenaar
Louk T. Timmer
Eva van Rooij
ResearchOpen Access29 Jan 2021
Communications Biology

Volume: 4, P: 1-15
Evolutionary pressures on microbial metabolic strategies in the chemostat

Meike T. Wortel
Evert Bosdriesz
Frank J. Bruggeman
ResearchOpen Access06 Jul 2016
Scientific Reports

Volume: 6, P: 1-11
Modelling strategies for the industrial exploitation of lactic acid bacteria

Lactic acid bacteria (LAB) are extensively used in the food and chemical industries. Here, Bas Teusink and Eddy Smid discuss how global metabolic modelling approaches, encompassing metabolic engineering, functional genomics and mathematical analysis, can be applied to optimize the industrial applications of LAB.

Bas Teusink
Eddy J. Smid
Reviews01 Jan 2006
Nature Reviews Microbiology

Volume: 4, P: 46-56
Preoperative chemotherapy, radiotherapy and surgical decision-making in patients with borderline resectable and locally advanced pancreatic cancer

In this Review, Besselink and colleagues discuss preoperative chemotherapy, radiotherapy and surgical decision-making in patients with borderline resectable pancreatic cancer and locally advanced pancreatic cancer, including disease staging and response evaluation.

Thomas F. Stoop
Rutger T. Theijse
Marc G. Besselink
Reviews30 Nov 2023
Nature Reviews Gastroenterology & Hepatology

Volume: 21, P: 101-124
Development and external validation of a prediction model for overall survival after resection of distal cholangiocarcinoma

Ali Belkouz
Stijn Van Roessel
Heinz-Josef Klümpen
Research17 Jan 2022
British Journal of Cancer

Volume: 126, P: 1280-1288

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