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GPRC5A promotes lung colonization of esophageal squamous cell carcinoma

The mechanisms allowing early disseminated cancer cells colonize other tissues remain largely unknown. Here, authors show that GPRC5A axis drives esophageal squamous cell carcinoma lung seeding and metastasis, in a mechanism resembling trophoblast behavior during embryo implantation.

Hongyu Zhou
Licheng Tan
Xin-Yuan Guan
ResearchOpen Access16 Nov 2024
Nature Communications

Volume: 15, P: 1-19
Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation

TNF is an important driver of many inflammatory diseases. Zhou et al. demonstrate ILC3 production of the growth factor HB-EGF protects against TNF-mediated injury of the gut epithelium in inflammatory bowel disease.

Lei Zhou
Wenqing Zhou
Gregory F. Sonnenberg
Research31 Jan 2022
Nature Immunology

Volume: 23, P: 251-261
On the adsorption characteristics and mechanism of methylene blue by ball mill modified biochar

Jinxia Wang
Yunfeng Tan
Le Luo
ResearchOpen Access01 Dec 2023
Scientific Reports

Volume: 13, P: 1-12
PCMR: a comprehensive precancerous molecular resource

Yichun Xiong
Jiaqi Li
Meng Zhou
ResearchOpen Access01 Apr 2025
Scientific Data

Volume: 12, P: 1-9