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Showing 1–3 of 3 results
Advanced filters: Author: Benjamin Anstett Clear advanced filters

  • One hypothesis for the latitudinal diversity gradient is based on an assumption of stronger species interactions at lower latitudes. Here, Roesti et al. estimate pelagic fish predation from long-term fishing records and find evidence of stronger predation at higher latitudes and with lower fish species richness.

    • Marius Roesti
    • Daniel N. Anstett
    • Roi Holzman
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-7

  • Exome sequencing is used to investigate the role of mutations and copy number aberrations in metastatic castration-resistant prostate cancer, revealing recurrent mutations in multiple chromatin/histone modifying genes, as well as genes involved in androgen signalling.

    • Catherine S. Grasso
    • Yi-Mi Wu
    • Scott A. Tomlins
    Research
    Nature
    Volume: 487, P: 239-243

  • In the E. coli Hsp100/Hsp70 system, the M domain of ClpB is essential for ClpB cooperation with DnaK and DnaJ and for protein disaggregation, but its function was largely unknown. New biochemical and biophysical data now indicate that the M domain acts as a molecular toggle that reversibly interacts with the AAA-1 domain of ClpB to regulate ATP hydrolysis and protein disaggregation activities. Also in this issue, Seyffer et al. show how DnaK interactions with M domain further enhance ClpB activity.

    • Yuki Oguchi
    • Eva Kummer
    • Bernd Bukau
    Research
    Nature Structural & Molecular Biology
    Volume: 19, P: 1338-1346