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Advanced filters: Author: Benjamin O. Farnung Clear advanced filters

  • RAB-11-positive recycling endosomes participate in the establishment and maintenance of epithelial polarity. Zerial and colleagues carry out an in vivo image-based RNAi screen for factors that regulate recycling endosome positioning in Caenorhabditis elegans. They identify, among other candidates, PAR-5 as a key determinant of recycling endosome positioning and, thus, apicobasal polarity.

    • Julia Franziska Winter
    • Sebastian Höpfner
    • Marino Zerial
    Research
    Nature Cell Biology
    Volume: 14, P: 666-676