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Advanced filters: Author: Beomkyu Kim Clear advanced filters

  • The interaction between IgE and its receptor FcεRI underlies many allergic responses; here the structure and mechanism of a newly engineered DARPin inhibitor is presented, revealing that it not only blocks the receptor–ligand interaction but also dissociates already-formed complexes.

    • Beomkyu Kim
    • Alexander Eggel
    • Theodore S. Jardetzky
    Research
    Nature
    Volume: 491, P: 613-617