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Common variation at 10p12.31 near MLLT10 influences meningioma risk

Richard Houlston, Matthias Simon and colleagues report that common variation at 10p12.31 influences meningioma susceptibility. The risk variants are located upstream of MLLT10, which encodes an activator of Wnt-dependent transcription.

Sara E Dobbins
Peter Broderick
Richard S Houlston
Research31 Jul 2011
Nature Genetics

Volume: 43, P: 825-827
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

Richard Houlston and colleagues report results of a genome-wide association study of childhood acute lymphoblastic leukemia. Identified risk loci include IKZF1 on 7p12.2 and ARID5B on 10q21.2, which encode transcription factors involved in the differentiation of B-cell progenitors.

Elli Papaemmanuil
Fay J Hosking
Richard S Houlston
Research16 Aug 2009
Nature Genetics

Volume: 41, P: 1006-1010
Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

Richard Houlston, Gareth Morgan, Kari Hemminki and colleagues report the results of a genome-wide association study of multiple myeloma. They identify two regions influencing susceptibility to this hematological malignancy.

Peter Broderick
Daniel Chubb
Richard S Houlston
Research27 Nov 2011
Nature Genetics

Volume: 44, P: 58-61
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Ian Tomlinson, Richard Houlston, Malcolm Dunlop and colleagues report results of a large genome-wide association study of colorectal cancer. They identify four new risk loci and suggest that many more loci of similar effect size are likely to exist.

Richard S Houlston
Jeremy Cheadle
Ian P M Tomlinson
Research24 Oct 2010
Nature Genetics

Volume: 42, P: 973-977
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Richard Houlston and colleagues report a genome-wide association study for colorectal cancer. They report three loci newly associated with colorectal cancer, bringing the total number of common susceptibility loci to 20.

Malcolm G Dunlop
Sara E Dobbins
Richard S Houlston
Research27 May 2012
Nature Genetics

Volume: 44, P: 770-776
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

Richard Houlston and colleagues report results of a genome-wide association study of Hodgkin's lymphoma. They identify three new susceptibility loci at 2p16 (REL), 8q24 and 10p14 (GATA3) and confirm a strong role for the HLA region in disease etiology.

Victor Enciso-Mora
Peter Broderick
Richard S Houlston
Research31 Oct 2010
Nature Genetics

Volume: 42, P: 1126-1130

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Common variation at 10p12.31 near MLLT10 influences meningioma risk

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

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Common variation at 10p12.31 near MLLT10 influences meningioma risk

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

Search

Quick links