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Sono-activable and biocatalytic 3D-printed scaffolds for intelligently sequential therapies in osteosarcoma eradication and defect regeneration

Osteosarcoma often leads to severe complications, necessitating innovative treatments. Here, authors report a 3D-printed scaffold, HS-ICTO, integrating sono-activable and biocatalytic properties, which generates ROS for tumor eradication while promoting oxygen production to alleviate hypoxia, working towards both osteosarcoma treatment and bone repair.

Xiao Rong
Sutong Xiao
Chong Cheng
ResearchOpen Access04 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer

AXL is overexpressed and has been investigated as a therapeutic target in several cancer types, including lung cancer. Here the authors design AXLdirected CAR-T cells and show that their anti-tumor activity can be improved in combination with microwave ablation in preclinical lung cancer models.

Bihui Cao
Manting Liu
Zhenfeng Zhang
ResearchOpen Access19 Oct 2022
Nature Communications

Volume: 13, P: 1-16
Many-body cavity quantum electrodynamics with driven inhomogeneous emitters

Under strong excitation, inhomogeneously broadened solid-state emitters coupled with high cooperativity to a cavity demonstrate collectively induced transparency and dissipative many-body dynamics, resulting from cavity–ion coupling.

Mi Lei
Rikuto Fukumori
Andrei Faraon
Research26 Apr 2023
Nature

Volume: 617, P: 271-276
Emergent Weyl excitations in systems of polar particles

Systems with Weyl excitations can display very interesting physical phenomena. Here the authors demonstrate that Weyl excitations exist generically in 3D systems of dipolar particles following angular momentum transfer, and discuss how to observe them in cold alkaline-earth-atom systems.

Sergey V. Syzranov
Michael L. Wall
Ana Maria Rey
ResearchOpen Access12 Dec 2016
Nature Communications

Volume: 7, P: 1-7
Preliminary study on the influencing factors of shear wave elastography for peripheral nerves in healthy population

Xinyi Tang
Bihui Zhu
Li Qiu
ResearchOpen Access10 Mar 2021
Scientific Reports

Volume: 11, P: 1-9

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Sono-activable and biocatalytic 3D-printed scaffolds for intelligently sequential therapies in osteosarcoma eradication and defect regeneration

Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer

Many-body cavity quantum electrodynamics with driven inhomogeneous emitters

Emergent Weyl excitations in systems of polar particles

Preliminary study on the influencing factors of shear wave elastography for peripheral nerves in healthy population

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