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Showing 1–2 of 2 results
Advanced filters: Author: Bijan Etemad-Gilbertson Clear advanced filters

  • The immune receptor Transmembrane and immunoglobulin domain containing 2 (TMIGD2) mediates T-cell and nature killer cells co-stimulation upon B7-family HHLA2 engagement. Here, the authors show that TMIGD2 is expressed in Acute Myeloid Leukaemia stem cells regulating self-renewal and differentiation to facilitate leukemogenesis.

    • Hao Wang
    • R. Alejandro Sica
    • Xingxing Zang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Retinal vascular disease treatments involve frequent pharmacological intraocular administrations. Here the authors present a method to increase the half-life of injected drugs by fusing these to a hyaluronan-binding peptide, which might lead to less frequent retinal disease treatments.

    • Joy G. Ghosh
    • Andrew A. Nguyen
    • Michael Roguska
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-10