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Advanced filters: Author: Bijun Qiu Clear advanced filters

  • The transcription factor E2F1 controls the expression of multiple genes and is frequently overactivated in cancer. Here, the authors show that E2F1 is deubiquitinated by POH1 and that this enhances the role of E2F1 in cell survival, and contributes to the pathogenesis of liver cancer.

    • Boshi Wang
    • Aihui Ma
    • Yongzhong Liu
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-15