The authors demonstrate that the expression of SOCS-7 is decreased in (HCC) cells, as well as in patients, and overexpression of SOCS-7 significantly decreases the proliferation and migration of HCC cells and increases apoptosis in cultured HCC cells. An animal xenogeneic model shows that overexpression of SOCS-7 inhibits tumors, and knockout of SOCS-7 results in tumor growth.
- Peixin Huang
- Zhiying Zhao
- Jinglin Xia
