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Showing 1–2 of 2 results
Advanced filters: Author: Björn Udo Klink Clear advanced filters
  • The RalGAP complex is an important tumor suppressor that counteracts oncogenic Ras signaling. Here, Rasche, Klink and colleagues present the cryo-EM structure of RalGAP and provides insight into its mechanism and molecular function.

    • René Rasche
    • Björn Udo Klink
    • Daniel Kümmel
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12
  • The AAA ATPase Pex1/Pex6 fuels the enzyme import across the peroxisomal membrane. Defects in either ATPase in humans result in severe disorders and early death. Here, the authors provide a detailed cryo-EM structures of the complex in the process of translocating an endogenous substate.

    • Maximilian Rüttermann
    • Michelle Koci
    • Christos Gatsogiannis
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15