By sectioning and sequencing the prefrontal cortex of humans, chimpanzees and macaques, He et al. compiled comprehensive transcriptome atlases of cortical layers. The study provides scores of previously uncharacterized layer-marker genes and more than a hundred human-specific genes, implying that the human neocortex has evolved more than was previously appreciated.
- Zhisong He
- Dingding Han
- Philipp Khaitovich
