Nature Search

Effects of dietary choline on nicotinic acetylcholine receptors in brain

BARBARA J. MORLEY
GIL R. ROBINSON
RONALD J. BRADLEY
Research28 Apr 1977
Nature

Volume: 266, P: 848-850
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patients with high-risk clear cell renal cell carcinoma.

David A. Braun
Giorgia Moranzoni
Toni K. Choueiri
ResearchOpen Access05 Feb 2025
Nature

Volume: 639, P: 474-482
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Immunotherapy for advanced penile cancer — rationale and potential

In this Comment, McGregor and Sonpavde discuss the rationale and potential for immunotherapy in advanced penile squamous cell carcinoma, highlighting associations with human papillomavirus infection and a tumour-site agnostic immunotherapy indication, which form the basis of ongoing clinical trials.

Bradley McGregor
Guru Sonpavde
Comments & Opinion30 Aug 2018
Nature Reviews Urology

Volume: 15, P: 721-723
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

Sarcomatoid and rhabdoid tumours are highly aggressive forms of renal cell carcinoma that are also responsive to immunotherapy. In this study, the authors perform a comprehensive molecular characterization of these tumours discovering an enrichment of specific alterations and an inflamed phenotype.

Ziad Bakouny
David A. Braun
Toni K. Choueiri
ResearchOpen Access05 Feb 2021
Nature Communications

Volume: 12, P: 1-14
Testosterone suppression and recovery with abiraterone/prednisone monotherapy after early discontinuation of LHRH-A in hormone sensitive prostate cancer

Autumn Gagnon
Caiwei Zhong
Atish D. Choudhury
Research27 Oct 2025
Prostate Cancer and Prostatic Diseases

P: 1-4
Bone targeted therapy and skeletal related events in the era of enzalutamide and abiraterone acetate for castration resistant prostate cancer with bone metastases

Bradley McGregor
Li Zhang
Christopher Sweeney
Research03 Sept 2020
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 341-348
Publisher Correction: Testosterone suppression and recovery with abiraterone/prednisone monotherapy after early discontinuation of LHRH-A in hormone sensitive prostate cancer

Autumn Gagnon
Caiwei Zhong
Atish D. Choudhury
Amendments and Corrections18 Nov 2025
Prostate Cancer and Prostatic Diseases

P: 1-2
Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

John A. F. Zupancic
Gui-shuang Ying
Gui-shuang Ying
Research28 Feb 2020
Journal of Perinatology

Volume: 40, P: 1100-1108
A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma

Amin H. Nassar
Kent W. Mouw
David J. Kwiatkowski
ResearchOpen Access20 Dec 2019
British Journal of Cancer

Volume: 122, P: 555-563
Pseudoaneurysm in the muscular artery of the right gluteal region following a BM harvest

B A McGregor
D W Ririe
M B Osswald
Correspondence09 Feb 2009
Bone Marrow Transplantation

Volume: 44, P: 201
Prevention of bronchopulmonary dysplasia: a cross-sectional survey of clinical practices in Canada

Brooke Read
Guillaume Ethier
Amit Mukerji
Research23 Apr 2022
Journal of Perinatology

Volume: 42, P: 1255-1257

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