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Advanced filters: Author: Bradley Olinger Clear advanced filters

The secretome of senescent monocytes predicts age-related clinical outcomes in humans

Olinger, Banarjee et al. use several proteomic approaches to profile the senescent monocyte secretome and identify senescence-associated circulating proteins that associate with age- and obesity-related phenotypes in two independent aging studies.

Bradley Olinger
Reema Banarjee
Nathan Basisty
Research03 Jun 2025
Nature Aging

Volume: 5, P: 1266-1279
Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential

How the neural crest gains its pluripotency-like stem cell potential is unclear. Here, the authors show that the entire post-gastrula ectoderm maintains expression of pluripotency genes, leading to the high stem cell capacity in the neural crest.

Ceren Pajanoja
Jenny Hsin
Laura Kerosuo
ResearchOpen Access23 Sept 2023
Nature Communications

Volume: 14, P: 1-17

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The secretome of senescent monocytes predicts age-related clinical outcomes in humans

Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential

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