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Showing 1–2 of 2 results
Advanced filters: Author: Brandon Seychell Clear advanced filters

  • The main protease, a key enzyme of SARS-CoV-2, can protect itself from oxidative damage. Here, Reinke, Schubert, and colleagues used XFEL radiation to image the enzyme, revealing the disulfide and NOS/SONOS bonds that form in response to oxygen.

    • Patrick Y. A. Reinke
    • Robin Schubert
    • Thomas J. Lane
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10

  • Reinke et. al. show that targeting host proteins like cathepsins is a promising strategy for treating SARS-CoV-2 and other viral infections due to their mutational stability in contrast to highly mutable viral targets.

    • Patrick Y. A. Reinke
    • Edmarcia Elisa de Souza
    • Alke Meents
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-13