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Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages

Here the authors isolate monoclonal antibodies specific for Plasmodium vivax apical membrane antigen 1, and characterize the epitope of one antibody that inhibits invasion of reticulocytes and hepatocytes, and reduces liver infection in a mouse model.

Anna C. Winnicki
Melanie H. Dietrich
Christopher L. King
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-16
Cycling cancer persister cells arise from lineages with distinct programs

Lineage tracing by barcoding of individual cells using a lentivirus library shows that cycling and non-cycling drug-tolerant persister cells in cancer arise from different lineages with distinct transcriptional and metabolic programs.

Yaara Oren
Michael Tsabar
Aviv Regev
Research11 Aug 2021
Nature

Volume: 596, P: 576-582
Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy

Santiago Delgado-Tirado
Dhanesh Amarnani
Joseph F. Arboleda-Velasquez
ResearchOpen Access30 Nov 2020
Scientific Reports

Volume: 10, P: 1-15