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Showing 1–7 of 7 results
Advanced filters: Author: Brett Marinelli Clear advanced filters

  • Infection by coagulase-positive Staphylococcus aureus (S. aureus) is the most common cause of acute endocarditis, a destructive and progressive condition of heart valves. Here, Peter Panizzi and his colleagues have developed a targeted, noninvasive fluorescence or positron emission technology imaging strategy that uses an engineered analog of prothrombin that can detect S. aureus in vivo in the endocarditic vegetations that form as a result of bacterial colonization.

    • Peter Panizzi
    • Matthias Nahrendorf
    • Ralph Weissleder
    Research
    Nature Medicine
    Volume: 17, P: 1142-1146

  • In vivo silencing in specific cell types remains the main obstacle for therapeutic applications of siRNAs. Leuschner et al. now show that an optimized lipid nanoparticle delivers siRNA to inflammatory monocytes in mice and, when transporting CCR2 siRNA, has therapeutic effects in cardiovascular disease, cancer and transplant rejection.

    • Florian Leuschner
    • Partha Dutta
    • Matthias Nahrendorf
    Research
    Nature Biotechnology
    Volume: 29, P: 1005-1010

  • Triggering and sustaining fusion reactions — with the goal of overall energy production — in a tokamak plasma requires efficient heating. Radio-frequency heating of a three-ion plasma is now experimentally shown to be a potentially viable technique.

    • Ye. O. Kazakov
    • J. Ongena
    • I. Zychor
    Research
    Nature Physics
    Volume: 13, P: 973-978

  • Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

    • V. Khachatryan
    • A.M. Sirunyan
    • E. Pesen
    ResearchOpen Access
    Nature
    Volume: 522, P: 68-72