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Showing 1–4 of 4 results

Advanced filters: Author: Bridget Simonson Clear advanced filters

Large-scale single-nuclei profiling identifies role for ATRNL1 in atrial fibrillation

Characterizing atrial fibrillation (AF) at the single cell level is challenging. Here, the authors perform snRNA-seq on 18 patients with AF to investigate the cell composition, and gene expression shifts associated with this common arrhythmia.

Matthew C. Hill
Bridget Simonson
Patrick T. Ellinor
ResearchOpen Access19 Nov 2024
Nature Communications

Volume: 15, P: 1-16
Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases

Genome-wide association meta-analyses identify more than 350 loci associated with atrial fibrillation. A polygenic score derived from these results improves atrial fibrillation risk prediction compared to published clinical and polygenic scores.

Carolina Roselli
Ida Surakka
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 539-547
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy

Mark Chaffin
Irinna Papangeli
Patrick T. Ellinor
Research22 Jun 2022
Nature

Volume: 608, P: 174-180
Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders

Vassilios J. Bezzerides
Aifeng Zhang
Anthony Rosenzweig
ResearchOpen Access23 Mar 2017
Scientific Reports

Volume: 7, P: 1-13