Nature Search

A companion quasar to 3C345

Bruce Margon
Gary A. Chanan
Ronald A. Downes
Research09 Apr 1981
Nature

Volume: 290, P: 480-481
Genes which control cell proliferation in the yeast Saccharomyces cerevisiae

Peter E. Sudbery
Andrew R. Goodey
Bruce L. A. Carter
Research27 Nov 1980
Nature

Volume: 288, P: 401-404
Rapid change in strontium isotopic composition of sea water before the Cretaceous/Tertiary boundary

Bruce K. Nelson
G. Kenneth MacLeod
Peter D. Ward
Research20 Jun 1991
Nature

Volume: 351, P: 644-647
Inactive complex formation between E. coli RNA polymerase and inhibitor protein purified from T7 phage infected cells

BRUCE A. HESSELBACH
DAI NAKADA
Research27 Nov 1975
Nature

Volume: 258, P: 354-357
The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor

Sutapa Mukherjee
Delia Nelson
Bruce WS Robinson
Research11 Sept 2001
Cancer Gene Therapy

Volume: 8, P: 580-588
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies

Associations between of omega-3 fatty acids and mortality are not clear. Here the authors report that, based on a pooled analysis of 17 prospective cohort studies, higher blood omega-3 fatty acid levels correlate with lower risk of all-cause mortality.

William S. Harris
Nathan L. Tintle
Dariush Mozaffarian
ResearchOpen Access22 Apr 2021
Nature Communications

Volume: 12, P: 1-9
Mitigation of SARS-CoV-2 transmission at a large public university

Safely opening university campuses has been a major challenge during the COVID-19 pandemic. Here, the authors describe a program of public health measures employed at a university in the United States which, combined with other non-pharmaceutical interventions, allowed the university to stay open in fall 2020 with limited evidence of transmission.

Diana Rose E. Ranoa
Robin L. Holland
Martin D. Burke
ResearchOpen Access09 Jun 2022
Nature Communications

Volume: 13, P: 1-16
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Crigler-Najjar Syndrome: An Unusual Course with Development of Neurologic Damage at Age Eighteen

Terrence F Blaschke
Paul D Berk
Jeanne G Waggoner
Research01 May 1974
Pediatric Research

Volume: 8, P: 573-590
Associations of autozygosity with a broad range of human phenotypes

Inbreeding depression has been observed in many different species, but in humans a systematic analysis has been difficult so far. Here, analysing more than 1.3 million individuals, the authors show that a genomic inbreeding coefficient (FROH) is associated with disadvantageous outcomes in 32 out of 100 traits tested.

David W Clark
Yukinori Okada
James F Wilson
ResearchOpen Access31 Oct 2019
Nature Communications

Volume: 10, P: 1-17
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones

The heterogeneity of androgen receptor (AR) gene alterations across metastases in prostate cancer remains unresolved. Here, the authors characterise AR genomic complexity across spatially separated lethal metastases from 10 prostate cancer patients and investigate how AR alterations evolve.

A. M. Mahedi Hasan
Paolo Cremaschi
Gerhardt Attard
ResearchOpen Access10 Aug 2023
Nature Communications

Volume: 14, P: 1-16
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

Chronic inflammation, marked by C-reactive protein, has been associated with changes in methylation, but the causal relationship is unclear. Here, the authors perform a Epigenome-wide association meta-analysis for C-reactive protein levels and find that these methylation changes are likely the consequence of inflammation and could contribute to disease.

Matthias Wielscher
Pooja R. Mandaviya
Marjo-Riitta Järvelin
ResearchOpen Access03 May 2022
Nature Communications

Volume: 13, P: 1-14
CRISPR based editing of SIV proviral DNA in ART treated non-human primates

Removal of integrated HIV DNA remains a roadblock for HIV cure. Here, Mancuso et al. show that intravenous administration of an adeno-associated virus-based CRISPR/Cas9 gene editing construct to SIV-infected macaques results in excision of integrated proviral DNA from infected blood cells and tissues known to be viral reservoirs.

Pietro Mancuso
Chen Chen
Kamel Khalili
ResearchOpen Access27 Nov 2020
Nature Communications

Volume: 11, P: 1-11
The political biogeography of migratory marine predators

Daily location data on the individuals of 14 migratory marine species from 2000 to 2009 allow annual migratory cycles to be mapped to the time spent in the high seas and the exclusive economic zones of specific countries, providing a basis for international management strategies for these species.

Autumn-Lynn Harrison
Daniel P. Costa
Barbara A. Block
Research03 Sept 2018
Nature Ecology & Evolution

Volume: 2, P: 1571-1578
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Analysis of blood pressure data from the Million Veteran Program trans-ethnic cohort identifies common and rare variants, and genetically predicted gene expression across multiple tissues associated with systolic, diastolic and pulse pressure in over 775,000 individuals.

Ayush Giri
Jacklyn N. Hellwege
Todd L. Edwards
Research21 Dec 2018
Nature Genetics

Volume: 51, P: 51-62
Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Whole-genome sequencing analysis of individuals with primary immunodeficiency identifies new candidate disease-associated genes and shows how the interplay between genetic variants can explain the variable penetrance and complexity of the disease.

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Research06 May 2020
Nature

Volume: 583, P: 90-95
Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1

Lesley J Bruce
Hannah C Robinson
Gordon W Stewart
Research09 Oct 2005
Nature Genetics

Volume: 37, P: 1258-1263
Immunotherapy and chemotherapy — a practical partnership

Richard A. Lake
Bruce W.S. Robinson
Reviews20 Apr 2005
Nature Reviews Cancer

Volume: 5, P: 397-405
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus

Wen Shi Lee
George Taiaroa
Adam K. Wheatley
ResearchOpen Access25 Apr 2025
npj Viruses

Volume: 3, P: 1-10
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

ApoE4 exacerbates tau pathogenesis, neuroinflammation and tau-mediated neurodegeneration independently of brain amyloid-β pathology, and exerts a ‘toxic’ gain of function whereas its absence is protective.

Yang Shi
Kaoru Yamada
David M. Holtzman
Research20 Sept 2017
Nature

Volume: 549, P: 523-527
Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disorder characterised by asthma, eosinophilia and vasculitis. Here, the authors describe a genome-wide association study of EGPA that reveals clinical and genetic differences between subgroups stratified by autoantibody status (ANCA).

Paul A Lyons
James E Peters
Kenneth G. C. Smith
ResearchOpen Access12 Nov 2019
Nature Communications

Volume: 10, P: 1-13
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Femtosecond time-delay X-ray holography

A modern version of Newton's 'dusty 'mirror' experiment is made, whereby X-ray pulses are focused on a thin membrane with polystyrene particles placed in front of an X-ray mirror. After a pulse traverses through the sample, triggering the explosion of a particle, it is reflected back on to the sample by the mirror to probe this reaction. The resulting diffraction pattern contains accurate time and spatially resolved information about the exploding particles.

Henry N. Chapman
Stefan P. Hau-Riege
Janos Hajdu
Research09 Aug 2007
Nature

Volume: 448, P: 676-679
Cross-priming in health and disease

The activation of cytotoxic T lymphocytes by cross-presented antigen (known as cross-priming) is necessary for immunity against certain viruses, bacteria and most tumours. Here, the underlying cellular and molecular mechanisms of cross-priming are described, providing insight into some central questions on the basic mechanisms of cross-priming, and its physiological and therapeutic importance are discussed.

Christian Kurts
Bruce W. S. Robinson
Percy A. Knolle
Reviews01 Jun 2010
Nature Reviews Immunology

Volume: 10, P: 403-414
Reducing the energy cost of human walking using an unpowered exoskeleton

The attachment of a simple, unpowered, mechanical exoskeleton to the foot and ankle results in a net saving of 7% of the metabolic energy expended in human walking.

Steven H. Collins
M. Bruce Wiggin
Gregory S. Sawicki
Research01 Apr 2015
Nature

Volume: 522, P: 212-215
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

Thomas W. Winkler
Humaira Rasheed
Iris M. Heid
ResearchOpen Access13 Jun 2022
Communications Biology

Volume: 5, P: 1-20
Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

Detailed clinical and virologic characteristics of the first 12 individuals with COVID-19 in the United States from the US Centers for Disease Control and Prevention.

Stephanie A. Kujawski
Karen K. Wong
Jing Zhang
Research23 Apr 2020
Nature Medicine

Volume: 26, P: 861-868
Precise interpolar phasing of abrupt climate change during the last ice age

A new ice core from West Antarctica shows that, during the last ice age, abrupt Northern Hemisphere climate variations were followed two centuries later by a response in Antarctica, suggesting an oceanic propagation of the climate signal to the Southern Hemisphere high latitudes.

Christo Buizert
Betty Adrian
Thomas E. Woodruff
Research08 Apr 2015
Nature

Volume: 520, P: 661-665
Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo

David W. Greening
Hong Ji
Richard J. Simpson
ResearchOpen Access08 Sept 2016
Scientific Reports

Volume: 6, P: 1-18
Responses of turkey vultures to unmanned aircraft systems vary by platform

Morgan B. Pfeiffer
Bradley F. Blackwell
Esteban Fernández-Juricic
ResearchOpen Access04 Nov 2021
Scientific Reports

Volume: 11, P: 1-13

Search

A companion quasar to 3C345

Genes which control cell proliferation in the yeast Saccharomyces cerevisiae

Rapid change in strontium isotopic composition of sea water before the Cretaceous/Tertiary boundary

Inactive complex formation between E. coli RNA polymerase and inhibitor protein purified from T7 phage infected cells

The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies

Mitigation of SARS-CoV-2 transmission at a large public university

Whole-genome sequencing reveals host factors underlying critical COVID-19

Crigler-Najjar Syndrome: An Unusual Course with Development of Neurologic Damage at Age Eighteen

Associations of autozygosity with a broad range of human phenotypes

Copy number architectures define treatment-mediated selection of lethal prostate cancer clones

DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

CRISPR based editing of SIV proviral DNA in ART treated non-human primates

The political biogeography of migratory marine predators

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1

Immunotherapy and chemotherapy — a practical partnership

Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Femtosecond time-delay X-ray holography

Cross-priming in health and disease

Reducing the energy cost of human walking using an unpowered exoskeleton

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

Precise interpolar phasing of abrupt climate change during the last ice age

Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo

Responses of turkey vultures to unmanned aircraft systems vary by platform

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