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Showing 1–6 of 6 results
Advanced filters: Author: Bryan Clary Clear advanced filters

  • Successive rounds of selection of an RNA library in a mouse cancer model resulted in the identification of an aptamer that specifically bound a cancer-associated protein, providing an in vivo approach for identifying RNA motifs that can reveal and potentially inhibit tumor-specific targets.

    • Jing Mi
    • Yingmiao Liu
    • Bryan M Clary
    Research
    Nature Chemical Biology
    Volume: 6, P: 22-24

  • The cellular organelles peroxisomes contribute to the sensitivity of cells to ferroptosis by synthesizing polyunsaturated ether phospholipids, and changes in the abundances of these lipids are associated with altered sensitivity to ferroptosis during cell-state transitions.

    • Yilong Zou
    • Whitney S. Henry
    • Stuart L. Schreiber
    Research
    Nature
    Volume: 585, P: 603-608

  • Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes, including immune, metabolic, stress response and mitochondrial pathways.

    • David Amar
    • Nicole R. Gay
    • Elena Volpi
    ResearchOpen Access
    Nature
    Volume: 629, P: 174-183

  • It is known that exercise influences many human traits, but not which tissues and genes are most important. This study connects transcriptome data collected across 15 tissues during exercise training in rats as part of the Molecular Transducers of Physical Activity Consortium with human data to identify traits with similar tissue specific gene expression signatures to exercise.

    • Nikolai G. Vetr
    • Nicole R. Gay
    • Stephen B. Montgomery
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14