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Advanced filters: Author: Céline Méaudre Clear advanced filters

EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition

Cells carrying EZH2 mutations found in lymphoma show a specific transcriptional response to PRC2 inhibition. A longitudinal study reveals unexpected genetic heterogeneity in follicular lymphomas, with implications for therapeutic strategies.

Pierre Romero
Laia Richart
Raphaël Margueron
ResearchOpen Access24 Apr 2024
Nature Communications

Volume: 15, P: 1-19

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EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition

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