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Showing 1–8 of 8 results

Advanced filters: Author: C B Verchere Clear advanced filters

β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment

Liam R Brunham
Janine K Kruit
Michael R Hayden
Research18 Feb 2007
Nature Medicine

Volume: 13, P: 340-347
A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models

β-cell dysfunction in type 2 diabetes is associated with pathological aggregates of IAPP that accumulate in pancreatic islets. Here, the authors describe a novel antibody cloned from healthy elderly donors that selectively targets IAPP oligomers and protects from IAPP toxicity.

Fabian Wirth
Fabrice D. Heitz
Jan Grimm
ResearchOpen Access09 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Complexity of the eukaryotic dolichol-linked oligosaccharide scramblase suggested by activity correlation profiling mass spectrometry

Alice Verchère
Andrew Cowton
Anant K. Menon
ResearchOpen Access14 Jan 2021
Scientific Reports

Volume: 11, P: 1-14
TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells

M R Moniri
X-Y Sun
G L Warnock
Research06 Jul 2012
Cancer Gene Therapy

Volume: 19, P: 652-658
AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells

Eva Tudurí
Maria M. Glavas
Timothy J. Kieffer
ResearchOpen Access25 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects

Adam Ramzy
Eva Tudurí
Timothy J. Kieffer
ResearchOpen Access29 Jun 2020
Scientific Reports

Volume: 10, P: 1-14
Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter

Patricia P. M. Mathiassen
Anant K. Menon
Thomas Günther Pomorski
ResearchOpen Access13 Jul 2021
Scientific Reports

Volume: 11, P: 1-14
Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction

B R Tennant
B Vanderkruk
B G Hoffman
ResearchOpen Access19 May 2016
Cell Death & Disease

Volume: 7, P: e2233