Comparisons of patients' and clinicians' reports of adverse effects during clinical trials frequently reveal underreporting by clinicians and a discord between the severities of the adverse effects experienced by patients and estimates from clinicians. Despite this situation, few trials include patient-reported outcome measures (PROMs). In this Perspectives, the authors compare and discuss the use of such measures in clinical trials in men with prostate cancer over the past 5 years, highlighting a need for greater use of PROMs.
- Lesley Fallowfield
- Heather Payne
- Valerie Jenkins
