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Oncogene (5)
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Showing 1–17 of 17 results

Advanced filters: Author: C Ronchini Clear advanced filters

Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

Brian J Nickoloff
Barbara A Osborne
Lucio Miele
Reviews03 Oct 2003
Oncogene

Volume: 22, P: 6598-6608
Soft X-ray prompt emission from the high-redshift gamma-ray burst EP240315a

The death of massive stars has traditionally been discovered by explosive events in the gamma-ray band. Liu et al. show that the sensitive wide-field monitor on board Einstein Probe can reveal a weak soft-X-ray signal much earlier than gamma rays.

Y. Liu
H. Sun
X.-X. Zuo
Research23 Jan 2025
Nature Astronomy

Volume: 9, P: 564-576
Spectral index-flux relation for investigating the origins of steep decay in γ-ray bursts

Gamma ray bursts (GRB) are transient events releasing large amount of energy. Here, the authors show a relation between the spectral index and the flux, which allows further investigation of the origin of steep decay in GRBs.

Samuele Ronchini
Gor Oganesyan
Om Sharan Salafia
ResearchOpen Access07 Jul 2021
Nature Communications

Volume: 12, P: 1-9
Exceptionally bright optical emission from a rare and distant gamma-ray burst

A luminous optical flash from GRB 210619B was captured rapidly by robotic telescopes and attributed to an extremely fast, narrow and magnetized jet shocked by propagating into the surrounding medium.

Gor Oganesyan
Sergey Karpov
Michael Prouza
Research11 May 2023
Nature Astronomy

Volume: 7, P: 843-855
Gigaelectronvolt emission from a compact binary merger

The observation of transient-like gigaelectronvolt emission in the high-energy gamma-rays of GRB 211211A, from the merger of two compact binary objects, is reported.

Alessio Mei
Biswajit Banerjee
Pawan Tiwari
Research07 Dec 2022
Nature

Volume: 612, P: 236-239
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

After expression of the PML–RAR oncogene in haematopoietic stem cells, p21 is necessary to limit cell cycle progression and thus limit the accumulation of DNA damage which would otherwise limit the self-renewal of leukaemic stem cells and prevent the development of leukaemia

Andrea Viale
Francesca De Franco
Pier Giuseppe Pelicci
Research01 Jan 2009
Nature

Volume: 457, P: 51-56
Computational challenges for multimodal astrophysics

Multi-messenger astronomy offers promises for exploring Universe events in distance. Nevertheless, there are numerous computational challenges when analyzing the massive heterogeneous messenger data from various detectors, creating research opportunities to the community, such as developing multimodal machine learning.

Elena Cuoco
Barbara Patricelli
Filip Morawski
Reviews22 Aug 2022
Nature Computational Science

Volume: 2, P: 479-485
Notch-1 activates estrogen receptor-α-dependent transcription via IKKα in breast cancer cells

L Hao
P Rizzo
L Miele
Research19 Oct 2009
Oncogene

Volume: 29, P: 201-213
Inhibition of γ-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells

S Rasul
R Balasubramanian
R C Coombes
ResearchOpen Access09 Jun 2009
British Journal of Cancer

Volume: 100, P: 1879-1888
ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor

C Osipo
P Patel
L Miele
Research12 May 2008
Oncogene

Volume: 27, P: 5019-5032
Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model

J J Arcaroli
K S Quackenbush
W A Messersmith
ResearchOpen Access18 Jul 2013
British Journal of Cancer

Volume: 109, P: 667-675
Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1

K Takahashi
H Akiyama
T Uchida
Research11 Dec 2006
Oncogene

Volume: 26, P: 3835-3845
Erratum: Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

L Riva
C Ronchini
P G Pelicci
Amendments and Corrections21 Mar 2014
Blood Cancer Journal

Volume: 4, P: e195
New wirings in the survivin networks

D C Altieri
Reviews20 Oct 2008
Oncogene

Volume: 27, P: 6276-6284
PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias

C Ronchini
A Brozzi
P G Pelicci
Research27 Dec 2016
Leukemia

Volume: 31, P: 1975-1986
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

L Riva
C Ronchini
P G Pelicci
CorrespondenceOpen Access13 Sept 2013
Blood Cancer Journal

Volume: 3, P: e147
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia

A G Sanarico
C Ronchini
F Bernassola
ResearchOpen Access06 Dec 2017
Leukemia

Volume: 32, P: 911-919