Rajagopal et al. show that transient, intracellular temperature spikes coincide well with electrical heating from proton transport across the mitochondrial membrane in Aplysia neurons. A lack of sustained temperature rise suggests that a transient dissipation of proton motive force rather than substrate oxidation may play a dominant role for heat generation.
- Manjunath C. Rajagopal
- Jeffrey W. Brown
- Sanjiv Sinha
