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Showing 1–2 of 2 results
Advanced filters: Author: C. Trollet Clear advanced filters

  • Oculopharyngeal muscular dystrophy is caused by trinucleotide repeat expansions in thePABPN1gene. Here the authors use AAV-based gene therapy to knockdown the mutant gene and replace it with a wild-type allele, and show effectiveness in mice and in patient cells.

    • A. Malerba
    • P. Klein
    • G. Dickson
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • Lenz, Roncalli and colleagues examine the difference in transcriptional phenotype in Calanus finmarchicus during reproductive and dormant phases. Their findings indicate gene targets for assessment of reproductive strategies in this high latitude copepod crucial to marine food webs.

    • Petra H. Lenz
    • Vittoria Roncalli
    • Daniel K. Hartline
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-13