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Showing 1–6 of 6 results
Advanced filters: Author: CH Arrowsmith Clear advanced filters

  • As Nature Chemical Biology approaches its third decade we asked a collection of chemical biologists, “What do you think are the most exciting frontiers or the most needed developments in your main field of research?” — here is what they said.

    • Lona M. Alkhalaf
    • Cheryl Arrowsmith
    • Georg Winter
    Special Features
    Nature Chemical Biology
    Volume: 21, P: 6-15

  • Relativistic electron-positron (pair) plasmas play a fundamental role in the magnetospheres, jets, and winds of black holes and neutron stars, but existing studies have been purely theoretical. Here, the authors open up the exciting possibility to probe relativistic pair-plasmas in the laboratory.

    • C. D. Arrowsmith
    • P. Simon
    • G. Gregori
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-8

  • Harding et al. present a biophysical and structural characterization of the complex between huntingtin (HTT) and HAP40 proteins. They show that the abundance of HAP40 is coupled with that of HTT and that there is greater conformational variety in the exon 1 of the mutant HTT than WT, important for the future drug discovery studies targeting Huntington’s disease.

    • Rachel J. Harding
    • Justin C. Deme
    • Cheryl H. Arrowsmith
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-16

  • The Structural Genomics Consortium (SGC) and its clinical, industry and disease-foundation partners are launching open-source preclinical translational medicine studies.

    • Aled M. Edwards
    • Cheryl H. Arrowsmith
    • L. Trevor Young
    Comments & Opinion
    Nature Reviews Drug Discovery
    Volume: 14, P: 149-150