Spitrobot is a protein crystal plunging system that enables reaction quenching through cryo-trapping with millisecond time resolution. Here, the authors present Spitrobot 2 as an integrated benchtop device with improved net sample preparation time and cryo-trapping delay time, increasing the number of target systems that can be studied using cryo-trapping time-resolved crystallography.
- Maria Spiliopoulou
- Caitlin E. Hatton
- Eike C. Schulz