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Advanced filters: Author: Caitlin N. Spaulding Clear advanced filters

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

Both F17-like and type 1 pili promote intestinal colonization in mouse colonic crypts, and the high-affinity mannoside M4284 reduces intestinal colonization of uropathogenic Escherichia coli while simultaneously treating urinary tract infections without disrupting the composition of the gut microbiota.

Caitlin N. Spaulding
Roger D. Klein
Scott J. Hultgren
Research14 Jun 2017
Nature

Volume: 546, P: 528-532
Precision antimicrobial therapeutics: the path of least resistance?

Caitlin N. Spaulding
Roger D. Klein
Scott J. Hultgren
ReviewsOpen Access27 Feb 2018
npj Biofilms and Microbiomes

Volume: 4, P: 1-7

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Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

Precision antimicrobial therapeutics: the path of least resistance?

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