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Showing 1–2 of 2 results
Advanced filters: Author: Caleb Heffner Clear advanced filters

  • The cre-loxP system is widely used for the generation of conditional gene knockouts. Here Heffner et al.systematically characterize cre recombinase activity in tissues of embryonic and adult cre-driver mouse strains and provide an online resource for scientists.

    • Caleb S. Heffner
    • C. Herbert Pratt
    • Stephen A. Murray
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-9

  • Exome sequencing of 851 trios from more than 2,500 individuals finds 187 genes with de novo mutations that contribute to meningomyelocele (spina bifida) and highlights critical pathways required for neural tube closure.

    • Yoo-Jin Jiny Ha
    • Ashna Nisal
    • Joseph G. Gleeson
    Research
    Nature
    Volume: 641, P: 419-426