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Reply to: Increases in the world’s most extreme wildfire events probably driven by fire size and simultaneity

Calum X. Cunningham
Grant J. Williamson
David M. J. S. Bowman
Research09 Jun 2025
Nature Ecology & Evolution

Volume: 9, P: 1341-1344
Wildfires will intensify in the wildland-urban interface under near-term warming

The intensity of wildfires is projected to rise across 88% of global fire-prone areas under 1.5°C warming, with the largest increases expected in wildland-urban interfaces already prone to disasters, based on modelled fire radiative power in response to projected fire weather.

Calum X. Cunningham
John T. Abatzoglou
David M. J. S. Bowman
ResearchOpen Access09 Jul 2025
Communications Earth & Environment

Volume: 6, P: 1-9
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

Shilpa Nadimpalli Kobren
Mikhail A. Moldovan
Shamil R. Sunyaev
ResearchOpen Access07 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Increasing frequency and intensity of the most extreme wildfires on Earth

Analysis of fire radiative power derived from satellite data finds that the frequency of extreme fire events increased 2.2-fold from 2003 to 2023 and that these increases were mostly driven by extreme fires in temperate conifer and boreal forest biomes.

Calum X. Cunningham
Grant J. Williamson
David M. J. S. Bowman
Research24 Jun 2024
Nature Ecology & Evolution

Volume: 8, P: 1420-1425
Landscape heterogeneity buffers the impact of an extreme weather event on wildlife

Using weather data combined with multi-decadal caribou and wolf demographic data, heterogeneous habitat and topography are shown to mitigate the impact of an extreme precipitation event on wildlife populations in Alaska.

Laura R. Prugh
Jessica D. Lundquist
Michael T. Durand
ResearchOpen Access15 Nov 2024
Communications Biology

Volume: 7, P: 1-11
Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment

Marie Morimoto
Vikas Bhambhani
May Christine V. Malicdan
ResearchOpen Access10 Feb 2023
npj Genomic Medicine

Volume: 8, P: 1-16
An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Sacha Ferdinandusse
Kirsty McWalter
Frédéric M. Vaz
ResearchOpen Access26 Nov 2020
Genetics in Medicine

Volume: 23, P: 740-750
Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11

Thomas A. Ravenscroft
Jennifer B. Phillips
Hugo J. Bellen
Research10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1889-1900

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Reply to: Increases in the world’s most extreme wildfire events probably driven by fire size and simultaneity

Wildfires will intensify in the wildland-urban interface under near-term warming

Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Increasing frequency and intensity of the most extreme wildfires on Earth

Landscape heterogeneity buffers the impact of an extreme weather event on wildlife

Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment

An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11

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