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Showing 1–6 of 6 results
Advanced filters: Author: Cameron J. Morse Clear advanced filters
  • Understanding the mechanical properties of DNA helps us to predict protein–DNA and DNA–DNA interactions. It is now shown that—with the aid of statistical physics—the melting temperature of DNA can be used to extract very detailed information about local flexibility.

    • Gerald Weber
    • Jonathan W. Essex
    • Cameron Neylon
    Research
    Nature Physics
    Volume: 5, P: 769-773
  • Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic.

    • Jay J. Van Bavel
    • Aleksandra Cichocka
    • Paulo S. Boggio
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14
  • Singlet fission may one day allow solar cells to produce two excited electrons with one photon. Now, by comparison of the time-resolved photoluminescence and sensitized triplet–triplet annihilation of a tetracene derivative, it has been shown that—contrary to previous reports—the excimer state is a trap, and not a necessary intermediate for singlet fission.

    • Cameron B. Dover
    • Joseph K. Gallaher
    • Timothy W. Schmidt
    Research
    Nature Chemistry
    Volume: 10, P: 305-310
  • Most studies of autism spectrum disorder (ASD) have focused on neuronal mechanisms. Here, the authors describe vascular impairments in a mouse model of 16p11.2 deletion syndrome using physiological and genetic approaches to examine endothelial-dependent phenotypes.

    • Julie Ouellette
    • Xavier Toussay
    • Baptiste Lacoste
    Research
    Nature Neuroscience
    Volume: 23, P: 1090-1101
  • A new approach is used to target BET family bromodomains which are found in transcriptional regulators where they mediate the recognition of acetyl-lysine chromatin marks. Structural data reveal how the compound JQ1 binds to the bromodomain of BRD4. BRD4 has been implicated in a subtype of human squamous carcinomas, and JQ1 is found to inhibit the growth of BRD4 dependent tumours in mouse models.

    • Panagis Filippakopoulos
    • Jun Qi
    • James E. Bradner
    Research
    Nature
    Volume: 468, P: 1067-1073