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Showing 1–2 of 2 results
Advanced filters: Author: Carissa P. Olsen Clear advanced filters

  • Here, Diot et al. use the nematode Caenorhabditis elegans as a model to identify off-target toxicity mechanisms for tamoxifen, and find that these include fatty acid metabolism and cell death, which can be modulated by different bacterial species.

    • Cédric Diot
    • Aurian P. García-González
    • Albertha J. M. Walhout
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).

    • Anthony O. Beas
    • Patricia B. Gordon
    • Daniel E. Gottschling
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10