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Kornfeld-Sylla et al reveal how alpha brainwaves are altered in children and adults with Fragile X Syndrome (FXS) and find parallel changes in alpha-like rhythms in juvenile and adult FXS model mice, showing their use for testing potential therapies.

Next week, exhibitors from all over Europe will converge on Amsterdam, the Netherlands, for the 4th European Congress on Biotechnology, ready to show off their bioreactors, chromatographs, and products for molecular biology.

Techniques to tease tissues into growing in non-native environs will be the focus of the Tissue Culture Association meeting next week in Las Vegas, Nevada. A preview of the exhibits is below.

Highlights from the Salon du Laboratoire and Interchemie '86 in Paris, and from the American Society for Cell Biology meeting in Washington, DC

Tissue culturists of every type and description will be in Washington, D. C. for next week's US Tissue Culture Association meeting on 27–30 May. Below are some of the products they will see on a stroll through the exhibit hall.

From specialized wordprocessing to data crunching, laboratories have complex computer needs. Here is an example of software products on show at the Scientific Computing and Automation Conference, 13–15 May, in Amsterdam, the Netherlands.

Biotechnologists of every stripe will be travelling to Miami, Florida next week for the Miami Bio/Technology Winter Symposium. A sampling of the products to be on display in the exhibit hall are below.

Next week, learning and memory, psychotherapeutic drugs and the ion channels of neurons will be the talk of the town at the American Society for Neuroscience meeting in Toronto, Ontario. As a preview to the more than 175 exhibits, we feature products from a neuro-receptor ligand to a magnetometer for mapping the brain.

The 27th annual meeting of the American Society for Cell Biology will be held next week in St Louis, Missouri. Roughly 210 companies have booked exhibit booths, and some of the wares they will have on display are described below.

Next week, over 16,000 scientists will travel to Las Vegas, Nevada for the annual meetings of the Federation of American Societies for Experimental Biology and the American Society for Biological Chemistry and Molecular Biology. Selections from the more than 450 companies with exhibit booths are described below.

Next week in Prague, Czechoslovakia, the 14th International Congress of Biochemistry will convene. Products on display in the exhibit hall will cover the gamut from analytical instruments to production-scale equipment.

Neurobiology and neurochemistry will be the talk of the town in Miami next week during the Miami Bio/Technology Winter Symposium. Besides an array of patch-clamps and recorders, the exhibits will feature products for studying peptides, and the nucleotides which code for them.

Next week's meeting of the American Society of Biological Chemists in Philadelphia, Pennsylvania, will have over 200 exhibits. Here we preview some of the products on view.

Next week, 10,000 chemists will flock to New Orleans, Louisiana, for the American Chemical Society's annual meeting. Here are some of the products they will see in the over 400 exhibit booths.

This week's New on the Market feature ends with a glimpse of several of the products on display at next week's VIIth International Congress of Virology meeting in Edmonton, Alberta, Canada.

Nearly 100 exhibitors will be showing their wares at next week's 4th International Congress of Cell Biology in Montreal, Canada. Below are some selections from the booths, including media, cell lines, and microscopes.

Thousands of chemists will flock to Los Angeles, California next week for the annual meeting of the American Chemical Society. Over 250 companies will be exhibiting their products; selections from their booths are described below.

This week's feature on plastics and other disposables for laboratory use ends with a preview of several products to be exhibited next week at the American Society of Human Genetics meeting in San Diego, California.

Freeze dryers, fermenters and special media preparations are only a few of the products to be displayed at the American Society for Microbiology annual meeting next week in Miami Beach, Florida. Over 300 exhibitors will be in attendance.

Biologic agents that target tumor necrosis factor represent an attractive approach to the treatment of vasculitic diseases, especially those associated with granuloma formation. Available data on the use of these agents for individual vasculitic diseases, and the potential to apply these data to the care of vasculitis patients in clinical practice are discussed in this Review.

Severe congenital development defects such as Jeune syndrome can result from the malfunction of primary cilia and dynein. Here Schmidts et al. report unique biallelic null mutations in a gene encoding a dynein light chain, helping to explain the nature of ciliopathies in human patients.

Crystallographic, biophysical and in silico analyses indicate that the conformational state of the mechanosensitive channel MscS is determined by the reorganization, due to changes in membrane tension, of the lipids within and around the protein.

Patient-derived xenografts are important tools for cancer drug development. Here, the authors develop models from 22 non-small cell lung cancer patients. They show genomic differences between models created from different spatial regions of tumours and a bottleneck on model establishment.

Mixed responses to targeted therapy within a patient are a clinical challenge. Here the authors show that TP53 loss-of-function cooperates with whole genome doubling which increases chromosomal instability. This leads to greater cellular diversity and multiple routes of resistance, which in turn promotes mixed responses to treatment.

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

In the TRACERx cohort of 171 patients with lung cancer, the ultrasensitive detection of ctDNA improves preoperative patient stratification, also in early-stage disease.