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Showing 1–10 of 10 results
Advanced filters: Author: Carolina Glas Clear advanced filters
  • Forest fragmentation is thought to reduce carbon storage at forest edges. Here, using remote sensing datasets, the authors show that biomass is 25% lower within 500 m of the forest edge, and suggest that fragmentation results in a global reduction in tropical forest carbon stocks by nearly 10%.

    • Rebecca Chaplin-Kramer
    • Ivan Ramler
    • Henry King
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-6
  • Analyses of tumor and bone marrow tissue from patients with glioblastoma demonstrate the presence of extracerebral niches that contained tumor-reactive and memory T cell subsets, including early stem-like phenotypes and stages, indicating antitumor CD8+ T cell differentiation in cranial bone marrow.

    • Celia Dobersalske
    • Laurèl Rauschenbach
    • Björn Scheffler
    ResearchOpen Access
    Nature Medicine
    Volume: 30, P: 2947-2956
  • Using awake and freely behaving mice, this study employs a high-throughput in vivo RNA-seq approach to identify odorant receptor repertoires. The authors find sets of odorant receptors for two odorants encompassing 69 odorant receptor-odor pairs and develop models to predict receptor activation.

    • Yue Jiang
    • Naihua Natalie Gong
    • Hiroaki Matsunami
    Research
    Nature Neuroscience
    Volume: 18, P: 1446-1454
  • Rivers are among the most diverse, dynamic, and productive ecosystems on Earth. Here, using Landsat imagery, the authors provide a global attribution of the recent changes in river regime to morphological dynamics, dam-induced widening, and hydrological signals.

    • Qianhan Wu
    • Linghong Ke
    • Chunqiao Song
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13
  • ALDH-2 inhibitors are a potential treatment for alcohol addiction. Now, Lina Yao et al. show that ALDH-2 inhibitors can reduce addiction to cocaine in rats by generating a dopamine metabolite called THP. THP inhibits an enzyme involved in dopamine synthesis, thereby blocking dopamine production in response to cocaine.

    • Lina Yao
    • Peidong Fan
    • Ivan Diamond
    Research
    Nature Medicine
    Volume: 16, P: 1024-1028
  • Kidney metabolism in disease is important but not well understood. Here, using isotope-guided metabolomics, the authors show that lysine’s metabolic activity conveys kidney protection in hypertension through accelerated metabolism and physiological effects on tubular function.

    • Markus M. Rinschen
    • Oleg Palygin
    • Alexander Staruschenko
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17
  • Carbapenem β-lactam antibiotics target non-classical transpeptidases, the L,D-transpeptidases, which act in an alternative Mycobacterium tuberculosis peptidoglycan synthesis pathway, informing the design of evolved carbapenems with improved antibacterial activity.

    • Pankaj Kumar
    • Amit Kaushik
    • Gyanu Lamichhane
    Research
    Nature Chemical Biology
    Volume: 13, P: 54-61
  • Heart failure is often a consequence of pathological growth of cardiomyocytes or cardiac hypertrophy. Here Ucar and colleagues report that the microRNAs miR-132 and miR-212 promote cardiac hypertrophy and inhibit autophagy in cardiomyocytes by downregulating the transcription factor FoxO3.

    • Ahmet Ucar
    • Shashi K. Gupta
    • Thomas Thum
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-11