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Showing 1–3 of 3 results
Advanced filters: Author: Caroline B Strømme Clear advanced filters

  • Chromatin reassembly after replication requires recycling of old and deposition of new histones. Structural insights into how MCM2, part of the replicative helicase, interacts with H3–H4 suggest a function in histone recycling at replication forks.

    • Hongda Huang
    • Caroline B Strømme
    • Dinshaw J Patel
    Research
    Nature Structural & Molecular Biology
    Volume: 22, P: 618-626

  • Histone chaperones safeguard the chromatin template and shield histones from promiscuous interactions to ensure their proper storage, transport, post-translational modification, nucleosome assembly and turnover.

    • Colin M. Hammond
    • Caroline B. Strømme
    • Anja Groth
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 18, P: 141-158

  • DNA replication requires re-establishment of chromatin structure, which involves incorporation of newly synthesized histones. Here, Klimovskaia et al.show that phosphorylation of the histone chaperone Asf1 by Tousled-Like Kinase stimulates its ability to bind histones, thus promoting chromatin assembly.

    • Ilnaz M. Klimovskaia
    • Clifford Young
    • Anja Groth
    Research
    Nature Communications
    Volume: 5, P: 1-13